Sökning: "repolarization"
Visar resultat 11 - 15 av 28 avhandlingar innehållade ordet repolarization.
11. Applications of Vectorcardiography for Diagnosis and Risk Stratification in Subpopulations at Risk for Life-Threatening Arrhythmias
Sammanfattning : Introduction: Vectorcardiography, or 3-dimensional electrocardiography is a tool which can be used to identify subtle changes in the electrical forces of the heart, and which can be applied to atrial depolarization, ventricular depolarization and ventricular repolarization for prognostic and diagostic purposes. Methods: Kor’s regression-related and quasi orthogonal methods was used to derive vectorcardiographic parameters from the 12-lead electrocardiogram and applied to a cohort of cryptogenic stroke patients to assess atrial fibrillation, hypertrophic cardiomyopathy patients to assess for ventricular arrhythmias, applied with right-precordial directed quasi orthogonal method to arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC/D) patients for diagnosis, and applied to ventricular repolarization only to patients with genotype-positive/phenotype-negative Long QT2 syndrome (KNCH2 mutation) to assess for cardiac events. LÄS MER
12. Novel approaches using electrocardiographic imaging for early detection of ARVC in patients and relatives and symptoms preceding sudden death
Sammanfattning : Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is an inherited disease of the myocardium, predominantly affecting the right ventricle (RV). Arrhythmias are common among patients with the disease and Sudden Cardiac Death (SCD) can occur even in early stages. LÄS MER
13. Myocardial electromechanical function in long QT syndrome
Sammanfattning : AIM: The aim of this thesis is to assess, in LQTS and according to genotype, the myocardial electromechanical (EM) function response to exercise, its relation to symptoms and its response to b-blocker therapy. To achieve this aim, we conducted 4 studies with the following specific objectives: i. LÄS MER
14. Antiarrhythmic and arrhythmic effects of an Ikr-blocking class III agent. A clinical and electrocardiographic study of almokalant
Sammanfattning : The interest in class III drugs has increased over the last decades as being potent antiarrhythmic agents in their mode of action by prolongation of repolarization and with no effect on conduction. Class I antiarrhythmic agents have proven effective in conversion of atrial fibrillation (AF), but may cause serious proarrhythmia. LÄS MER
15. Acute coronary syndromes. The prognostic importance of hypertension, diabetes and vectorcardiographic markers
Sammanfattning : Research questions: 1 Is hypertension and diabetes associated with the future risk of death, and recurrent manifestations of cardiovascular disease in acute coronary syndromes (ACS)? 2 How does myocardial ischemia affect depolarization and repolarization of the heart during the early phase of an acute myocardial infarction? 3 What is the prognostic value of accepted vectorcardiographic markers in relation to future risk of sudden cardiac death after ACS? Methodology: Papers I, III and IV studied patients with ACS prospectively and consecutively included at the coronary care unit of Sahlgrenska University Hospital. Paper I deals with 2,329 patients who were followed for a median of 8 years. LÄS MER
