Sökning: "repolarisation"

Visar resultat 6 - 10 av 13 avhandlingar innehållade ordet repolarisation.

  1. 6. Arrhythmogenic Right Ventricular Cardiomyopathy : Genetic and Electrocardiographic Aspects on Risk of Ventricular Arrhythmia and Diagnosis

    Författare :Anneli Svensson; Cecilia Gunnarsson; Pyotr Platonov; Perry M. Elliott; Linköpings universitet; []

    Sammanfattning : Introduction: ARVC (Arrhythmogenic Right Ventricular Cardiomyopathy) is a heritable rare disease of the heart muscle, primarily affecting the right ventricle, that may cause arrhythmias and heart failure.Aim: The overall aim of this thesis was to study various aspects of genetic information and electrocardiography (ECG), for their use in diagnosis and risk evaluation in ARVC. LÄS MER

  2. 7. Cell adhesion molecules during odontogenesis and tooth-related diseases

    Författare :Robert Heymann; Karolinska Institutet; Karolinska Institutet; []

    Sammanfattning : Cell adhesion molecules play essential roles in the development and disease of tooth and oral structures, as well as in the maintenance of adult tissue structure/function. It has been shown that different types of cell adhesion molecules (CAMs) play an important part in craniofacial development when ectomesenchymal cells migrate from the neural list to the primitive oral cavity, giving rise to the palatal processes and tooth germs. LÄS MER

  3. 8. Molecular pharmacology of amiodarone

    Författare :Viktor Drvota; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Amiodarone; thyroid hormone receptors; B-adrenergic receptors; AT-1 cardiomyocytes; Western blot; solution hybridization; Fura-2; Langendorff heart; mouse; guinea pig;

    Sammanfattning : MOLECULAR PHARMACOLOGY OF AMIODARONE Amiodarone (Am) is a potent class III antiarrhythmic drug. Its use is limited due to serious side effects and it was therefore used only when other therapeutic interventions proved to be ineffective. LÄS MER

  4. 9. Porcine myocardial ischemia-reperfusion studies on cardioprotection, ventricular arrhythmia and electrophysiology

    Författare :Jacob Odenstedt; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :porcine; myocardial ischemia; ventricular arrhythmia; sudden cardiac death; electrophysiology; vectorcardiography; endocardial mapping; spinal cord stimulation;

    Sammanfattning : Background: Coronary artery disease is the primary cause of death in adults in the industrialised world and ventricular fibrillation associated with myocardial ischemia is the main cause of sudden cardiac death. Restoration of blood flow and preservation of myocardial integrity throughout ischemia and reperfusion is essential to improve clinical outcome. LÄS MER

  5. 10. Structural and neurohormonal factors in left ventricular hypertrophy and inhibition of the renin-angiotensin-aldosterone system

    Författare :Karin Malmqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Left ventricular hypertrophy; RAAS; insulin; sympathetic nervous system; leptin echocardiography; soluble cell adhesion molecules; AT1-recemor blockade; ACE inhibitor; QT dispersion;

    Sammanfattning : Hypertensive left ventricular hypertrophy (LVH) is a major risk factor for cardiovascular morbidity and mortality. The aim of this thesis was to study how different neurohormonal systems relate to left ventricular mass, and to study structural and functional cardiovascular changes in hypertensive LVH. LÄS MER