Sökning: "repetitive motifs"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden repetitive motifs.

1. 1. Three Subfamilies of KRAB Zinc Finger Proteins : A Structural, Functional and Evolutionary Analysis

   Författare :Charlotta Mark; Lars Hellman; Fredrik Öberg; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Krüppel zinc finger; KRAB; TIF1β; transcriptional repression; Biologi; Biology; Biologi; Molecular Immunology; molekylär immunologi;

   Sammanfattning : Krüppel-related zinc finger proteins constitute the largest single class of transcription factors within the human genome. Members of this protein family have the ability to either activate or repress transcription depending on the presence of specific activator or repressor domains within the protein. LÄS MER

3. 2. The exploration and evolution of the avian genomic dark matter

   Författare :Valentina Peona; Alexander Suh; Hanna Johannesson; Rachel O'Neill; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; evolutionary genomics; genome assembly; sex chromosomes; birds; satellite DNA; transposable elements; endogenous retroviruses; Biology with specialization in Systematics; Biologi med inriktning mot systematik;

   Sammanfattning : The development and improvement of genome sequencing technologies in the last decade revolutionised the entire field of biology with genome assemblies of virtually any organism. Despite this tremendous progress, complex genomic regions are systematically missing from genome assemblies and form the so-called "genomic dark matter". LÄS MER

4. 3. Antibody Evolution and Repertoire Development

   Författare :Johan Lantto; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; serology; transplantation; Immunologi; serologi; virus neutralization; trinucleotide repeat; insertion; immunoglobulin variable genes; human cytomegalovirus; glycoprotein B; deletion; antibody; antibody repertoire;

   Sammanfattning : Antibodies are key players of the immune system in higher vertebrates, which provide a defense against potentially lethal threats from the environment. Besides their importance in the immune defense, antibodies have a great potential as reagents in biological chemistry and diagnostics, and as therapeutic agents against both infectious diseases and cancer. LÄS MER

5. 4. Regulation of the vertebrate transcriptome in development and disease

   Författare :Helena Storvall; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : In the last decade we have seen a tremendous development in the omics area (genomics, transcriptomics, proteomics etc.), making high throughput methods increasingly costeffective and available. LÄS MER

7. 5. Mammalian cell cycle regulation : characterisation of three genes expressed in proliferating cells

   Författare :Maria Starborg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cell cycle; DNA replication; licensing factor; mitosis; ceheckpoint regulator; centromere regions; cell proliferation marker; nucleolar protein; spermatogenesis;

   Sammanfattning : Proliferating cells undergo different phases in their life cycle. During interphase the cells grow and duplicate their DNA content, followed by a cell division phase, mitosis, which results in two daughter cells. LÄS MER