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Visar resultat 1 - 5 av 174 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Intestinal ischemia and reperfusion. Proinflammatory response and organ dysfunction

    Författare :Knut Olanders; Lund Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Kirurgi; ortopedi; traumatologi; orthopaedics; Surgery; inflammation; cytokine; leukocyte; reperfusion; ischemia; permeability; Intestine; endothelium;

    Sammanfattning : Intestinal I/R is considered to be an important initiating event in several pathophysiological conditions such as trauma, bleeding, sepsis and pancreatitis, frequently leading to concomitant both single and potentially multiple organ dysfunction. The purpose of this thesis was to study mechanims underlying the development of multiple organ dysfunction, with special focus on intercellular proinflammatory regulation in the concurrent development of tissue injury. LÄS MER

  3. 2. Improved bioenergetic recovery during experimental ischemia and reperfusion by irradiation

    Författare :Ann Lindgård; Göteborgs universitet; []
    Nyckelord :energy metabolism; skeletal muscle; monocyte; ischemia; reperfusion; NMR; singlet oxygen energy; light; LED;

    Sammanfattning : Prolonged ischemia and reperfusion frequently occur during clinical operations. The bioenergetic status decreases during ischemia and reactive oxygen species (ROS) are formed during reperfusion, which may lead to irreversible tissue injury. LÄS MER

  4. 3. Energy metabolism in skeletal muscle during ischemia and reperfusion. Experimental and clinical aspects

    Författare :Jonas Lundberg; Göteborgs universitet; []
    Nyckelord :energy metabolism; skeletal muscle; ischemia; reperfusion; MRS; hypothermia; singlet oxygen energy.;

    Sammanfattning : Microsurgical operations, using free vascularised transfer of tissues, induce an obligatory period of ischemia followed by reperfusion. The degree of ischemia and reperfusion injury is dependent on the ischemia time. LÄS MER

  5. 4. Renal Ischemia/Reperfusion Injury in Diabetes : Experimental Studies in the Rat

    Författare :Jan Melin; Bengt Rippe; Uppsala universitet; []
    Nyckelord :Medical sciences; diabetes mellitus; ischemia reperfusion; rat; end-stage renal disease; inflammation; fibrosis; hyaluronan; CD44; treatment; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Diabetes mellitus (DM) is one of the leading causes of end stage renal failure. An increased susceptibility to renal ischemia/reperfusion (I/R)-injury was found in DM rats. Unilateral renal ischemia for as short as 20 minutes led to an irreversible progressive injury in DM kidneys, whereas the injury in non-DM kidneys was almost reversible. LÄS MER

  7. 5. Hepatic ischemia-reperfusion injury

    Författare :Melroy Alistair D'Souza; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hepatic ischemia-reperfusion (I/R) injury is a complex phenomenon occuring in response to interruption of the liver’s blood and oxygen supply and the subsequent restoration of blood flow and tissue oxygenation. Techniques to reduce blood loss and other intra-operative manoeuvers during liver resection can cause hepatic I/R injury. LÄS MER