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Visar resultat 1 - 5 av 212 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Variation in length of proteins by repeats and disorder regions

   Författare :Rauan Sagit; Arne Elofsson; Andrey Kajava; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein length; repeats; domain repeats; protein evolution; duplication; tandem duplication; intrinsic disorder; intrinsically disordered; variation in length; insertion; deletion; recombination; expansion; contraction; Biochemistry; biokemi;

   Sammanfattning : Protein-coding genes evolve together with their genome and acquire changes, some of which affect the length of their protein products. This explains why equivalent proteins from different species can exhibit length differences. LÄS MER

3. 2. Intrinsic disorder and tandem repeats - match made in evolution : Computational studies of molecular evolution

   Författare :Oxana Lundström; Arne Elofsson; Liberles-Siltberg Jessica; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; intrinsically disordered proteins IDPs ; tandem repeats; short tandem repeats STRs ; genetic variation; orphan proteins; GC content; human STR variation; colorectal cancer; gene expression; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

   Sammanfattning : Proteins are both the building blocks and workers of the cell, carrying out most of the important functions. For a long time, their structure has been regarded as the primary factor for their function, but intrinsically disordered proteins demonstrate an alternative to this paradigm. LÄS MER

4. 3. Trinucleotide repeats and neuropsychiatric phenotypes

   Författare :Qiu-Ping Yuan; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Trinucleotide; repeat expansion; psychiatric disorder; gene; spastic paraplegia;

   Sammanfattning : Genetic studies of affective disorders have yielded several chromosomal regions suggestive for linkage. Linkage analysis was performed in five families with unipolar affective disorder, collected from northern Sweden. Four candidate regions on chromosomes 16, 18, 21 and 4p were excluded. LÄS MER

5. 4. Ressources linguistiques pour la gestion de l’intersubjectivité dans la parole en interaction : Analyses conversationnelles et phonétiques

   Författare :Rasmus Persson; Paul Touati; Richard Ogden; Lorenza Mondada; Franska; []
   Nyckelord :HUMANIORA; HUMANITIES; HUMANIORA; HUMANITIES; conversation analysis; French; talk-in-interaction; interaction; intersubjectivity; phonetics; prosody; intonation; accentuation; formulations; receipts; repetition; turn prefaces; repeats; repair; Humaniora; Språk och litteratur; Humanities; Languages and Literature; French; conversation analysis; talk-in-interaction; interaction; intersubjectivity; phonetics; prosody; intonation; accentuation; formulations; receipts; repetition; turn prefaces; repeats; repair;

   Sammanfattning : This dissertation deals with conversational practices through which interactants manage issues of intersubjectivity, i.e. mutual understanding for all practical purposes. LÄS MER

7. 5. Software Tools and Algorithms for Shotgun Sequence Assembly

   Författare :Martti T. Tammi; Bruce Roe; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Shotgun sequencing; multiple alignment; fragment assembly; repeats; sequencing error; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

   Sammanfattning : During the last ten years, a genomics revolution has changed the ways biological research is carried out. The draft sequence of the human genome is available, as well as the sequence of 84 other completed genomes. LÄS MER