Sökning: "renin inhibitor"

Visar resultat 1 - 5 av 19 avhandlingar innehållade orden renin inhibitor.

1. 1. Macula Densa Derived Nitric Oxide and Kidney Function

   Författare :Anna Ollerstam; Pontus Persson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Nitric oxide; rats; kidney; macula densa cells; tubuloglomerular feedback; renin; angiotensin II; blood pressure; hypertension; renal blood flow; neuronal nirtic oxide synthase; Cellbiologi; Cell biology; Cellbiologi; Physiology; fysiologi;

   Sammanfattning : The kidney is the major organ regulating the extracellular fluid volume and thereby the arterial blood pressure. The neuronal isoform of nitric oxide synthase (nNOS) in the kidney is predominantly located in the macula densa cells. LÄS MER

3. 2. Computer simulations of electronic energy transfer and a molecular dynamics study of a decapeptide

   Författare :Maria Lindberg; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Electronic energy transfer; Monte Carlo simulations; two-particle model; GAF-theory; anisotropic systems; fluorescence depolarization ratios; Brownian Dynamics; rotating donors; Molecular Dynamics; peptide; renin inhibitor;

   Sammanfattning : Electronic energy transfer has been investigated in pure donor systems by means of computer simulations. Calculated properties were the probability that the initially excited donor is excited at a time t after the excitation, Gs(t), the mean square displacement of the excitation and different fluorescence observables. LÄS MER

4. 3. Structural and neurohormonal factors in left ventricular hypertrophy and inhibition of the renin-angiotensin-aldosterone system

   Författare :Karin Malmqvist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Left ventricular hypertrophy; RAAS; insulin; sympathetic nervous system; leptin echocardiography; soluble cell adhesion molecules; AT1-recemor blockade; ACE inhibitor; QT dispersion;

   Sammanfattning : Hypertensive left ventricular hypertrophy (LVH) is a major risk factor for cardiovascular morbidity and mortality. The aim of this thesis was to study how different neurohormonal systems relate to left ventricular mass, and to study structural and functional cardiovascular changes in hypertensive LVH. LÄS MER

5. 4. Vascular and endothelial function in human hypertension, and the importance of the renin-angiotensin-aldosterone system

   Författare :Andreas Jekell; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Hypertension induces structural vascular and cardiac changes with increased arterial stiffness and left ventricular (LV) hypertrophy and is major risk factor for cardiovascular morbidity and mortality. The renin-angiotensin-aldosterone system (RAAS) and the sympathetic nervous system are important for blood pressure regulation and vascular function. LÄS MER

7. 5. Genetic aspects of stroke : association and linkage studies in a northern Swedish population

   Författare :Per-Gunnar Wiklund; Birgitta Stegmayr; Kjell Asplund; Dan Holmberg; Alun Evans; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; stroke; genetics; polymorphism; association; linkage; risk factors; plasminogen activator inhibitor-1; tissue plasminogen activator; angiotensin converting enzyme; angiotensin II receptor type 1; phosphodiesterase 4D; Invärtesmedicin; Internal medicine; Invärtesmedicin; medicin; Medicine;

   Sammanfattning : Stroke is a common, multifactorial cardiovascular disease. A stroke event is the result of traditional risk factors (i.e. hypertension, diabetes, smoking), environmental exposures and genetic factors in a complex interplay. LÄS MER