Sökning: "renal uptake"

Visar resultat 11 - 15 av 50 avhandlingar innehållade orden renal uptake.

  1. 11. Urinary Clara cell protein and alpha 1-microglobulin – biomarkers of changes in kidney and airway function

    Författare :Lena Andersson; Göteborgs universitet; []
    Nyckelord :biomarker; Clara cell 16 kDa protein CC16 ; alpha 1-microglobulin A1M ; ambient air pollution; renal function; pyelonephritis; children;

    Sammanfattning : Validated biomarkers are useful tools for screening large populations. The benefit of screening may be improved risk assessment or early indications of adverse effects before detection or onset of symptoms. LÄS MER

  2. 12. Tailoring Radionuclide Therapy of Neuroendocrine Tumors - Bridging the Gaps

    Författare :Anna Sundlöv; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 177Lu-DOTATATE; PRRT; somatostatin analogs; pituitary function; renal function; dosimetry; 68Ga-DOTATATE; individualized treatment; neuroendocrine tumors;

    Sammanfattning : Background and Aims: Radionuclide therapy is systemic, targeted radiotherapy. As such, we can apply the basic principles of radiobiology used in everyday practice in radiation oncology, as a means of tailoring the treatment to each patient and optimizing the balance between efficacy and toxicity. LÄS MER

  3. 13. Interaction between Adenosine and Angiotensin II in Renal Afferent Arterioles of Mice

    Författare :Enyin Lai; A. Erik G. Persson; Göran Bergström; Uppsala universitet; []
    Nyckelord :Physiology; adenosine; angiotensin II; afferent arteriole; calcium; nitric oxide; microperfusion; tubuloglomerular feedback; Fysiologi;

    Sammanfattning : Renal arterioles represent the most important effecter site in the control of renal perfusion and filtration. Adenosine (Ado), angiotensin II (Ang II) and nitric oxide (NO) interact in modulating arteriolar tone. The present work investigates the mechanism of this interaction. LÄS MER

  4. 14. Quantitation of gluconeogenesis in humans

    Författare :Karin Ekberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Gluconeogenesis; mass isotopomer distribution analysis; deuteratedwater; hexamethylenetetramine; splanchnic and renal glucose production;

    Sammanfattning : Several methods have been introduced for estimating gluconeogenesis, but none provides a direct measurement without assumptions that condition the accuracy of the estimate. The aim of this work has been to develop a new method for quantitative studies of gluconeogenesis, applicable in humans. LÄS MER

  5. 15. Cardiovascular and metabolic effects of endothelins in man : an experimental and clinical study

    Författare :Astrid Ottosson-Seeberger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :endothelin-1; big ET-1; C-terminal big ET-1 22-3 8 fragment; hemodynamic; blood flow; fractional extraction; conversion; plasma half-life; end-stage renal failure; ischemic heart disease; hemodialysis; high-flux membrane; glucose uptake; insulin sensitivity;

    Sammanfattning : Increased plasma concentrations of endothelin-1 (ET-1) and of its propeptide big endothelin-1 have been reported in diseases associated with endothelial dysfunction, cardiovascular remodelling and insulin resistance. In this thesis, we studied the hemodynamic effects of big ET-1 in healthy humans focusing on the mechanisms of the effects (study I-IV). LÄS MER