Sökning: "regulatory t cells"

Visar resultat 6 - 10 av 354 avhandlingar innehållade orden regulatory t cells.

  1. 6. Regulation of gut IgA induction by helper T cells

    Detta är en avhandling från Göteborgs universitet

    Författare :Inta Gribonika; Göteborgs universitet.; Gothenburg University.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosal immunology; secretory IgA; T regulatory cells; T follicular helper cells; Th17 cells; Peyer s patches; IgA class-switch recombination; germinal centers;

    Sammanfattning : The gut is the largest lymphoid organ in the body. Due to intense and constant exposure to the outside world, it also functions as the most important portal of entry for many pathogens. LÄS MER

  2. 7. Studies on the function of CD4CD25 regulatory T cells: An in vitro approach

    Detta är en avhandling från Section for Immunology, Lund University

    Författare :Lukas Cederbom; Lund University.; Lunds universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; CD152; Costimulation; Dendritic cells; Regulatory T cells; CD4 CD25 ; serology; transplantation; Immunologi; serologi;

    Sammanfattning : Immunological self-tolerance is a state of the whole organism where deleterious responses are either avoided or regulated. Breaking of immunological tolerance will lead to autoimmune disease or chronic inflammatory conditions. LÄS MER

  3. 8. The immortalization process of T cells with focus on the regulation of telomere length and telomerase activity

    Detta är en avhandling från Umeå : Umeå university

    Författare :Sofie Degerman; Umeå universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immortalization; senescence; T cells; Nijmegen breakage syndrome; telomere; telomerase; hTERT; generic aberrations; methylation; MEDICINE; MEDICIN; patologi; Pathology;

    Sammanfattning : Cellular immortalization is a major hallmark of cancer and is a multi-step process that requires numerous cell-type specific changes, including inactivation of control mechanisms and stabilization of telomere length. The telomeres at the chromosome ends are essential for genomic stability, and limit the growth potential of most cells. LÄS MER

  4. 9. The Multiple Faces of Genetically-Modified T Cells Potential Applications in Therapy

    Detta är en avhandling från Uppsala : Uppsala universitet

    Författare :Victoria Hillerdal; Uppsala universitet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer immunotherapy; genetically engineered T cells; chimeric antigen receptor; T cell receptor; antigen-specific T cells; immunotherapy; Immunologi; Immunology; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : In this PhD thesis the potential of T-cells as therapy for disease are explored. The applications of genetically modified T-cells for treatment of cancer and autoimmune disease; the functionality and optimal activation of T-cells are discussed. LÄS MER

  5. 10. Regulatory CD4+FOXP3+ T cells in Helicobacter pylori-induced disease

    Detta är en avhandling från Uppsala : Uppsala universitet

    Författare :Bert Kindlund; Göteborgs universitet.; Gothenburg University.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regulatory T cells; Helicobacter pylori; duodenal ulcer; gastric cancer; FOXP3;

    Sammanfattning : Helicobacter pylori colonize the gastric or duodenal mucosa of approximately half of the worlds’ population. Although most individuals are asymptomatic, H. pylori infection cause peptic ulcers or gastric cancer in 10-15 % and 1-2 %, respectively, of the infected individuals. LÄS MER