Sökning: "regulatory t cells"

Visar resultat 6 - 10 av 347 avhandlingar innehållade orden regulatory t cells.

  1. 6. The immortalization process of T cells with focus on the regulation of telomere length and telomerase activity

    Detta är en avhandling från Umeå : Umeå university

    Författare :Sofie Degerman; Umeå universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immortalization; senescence; T cells; Nijmegen breakage syndrome; telomere; telomerase; hTERT; generic aberrations; methylation; MEDICINE; MEDICIN; patologi; Pathology;

    Sammanfattning : Cellular immortalization is a major hallmark of cancer and is a multi-step process that requires numerous cell-type specific changes, including inactivation of control mechanisms and stabilization of telomere length. The telomeres at the chromosome ends are essential for genomic stability, and limit the growth potential of most cells. LÄS MER

  2. 7. The Multiple Faces of Genetically-Modified T Cells Potential Applications in Therapy

    Detta är en avhandling från Uppsala : Uppsala universitet

    Författare :Victoria Hillerdal; Uppsala universitet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer immunotherapy; genetically engineered T cells; chimeric antigen receptor; T cell receptor; antigen-specific T cells; immunotherapy; Immunologi; Immunology; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : In this PhD thesis the potential of T-cells as therapy for disease are explored. The applications of genetically modified T-cells for treatment of cancer and autoimmune disease; the functionality and optimal activation of T-cells are discussed. LÄS MER

  3. 8. Regulatory CD4+FOXP3+ T cells in Helicobacter pylori-induced disease

    Detta är en avhandling från Uppsala : Uppsala universitet

    Författare :Bert Kindlund; Göteborgs universitet.; Gothenburg University.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regulatory T cells; Helicobacter pylori; duodenal ulcer; gastric cancer; FOXP3;

    Sammanfattning : Helicobacter pylori colonize the gastric or duodenal mucosa of approximately half of the worlds’ population. Although most individuals are asymptomatic, H. pylori infection cause peptic ulcers or gastric cancer in 10-15 % and 1-2 %, respectively, of the infected individuals. LÄS MER

  4. 9. Regulatory T cells in human pregnancy

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Jenny Mjösberg; Linköpings universitet.; Linköpings universitet.; Östergötlands Läns Landsting.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : During pregnancy, fetal tolerance has to be achieved without compromising the immune integrity of the mother. CD4+CD25highFoxp3+ regulatory cells (Tregs) have received vast attention as key players in immune regulation. However, the identification of human Tregs is complicated by their similarity to activated nonsuppressive T cells. LÄS MER

  5. 10. MHCI-E mediated protection from IDDM on NOD mice : The role of regulatory T cells

    Detta är en avhandling från Stockholm : Stockholm University

    Författare :Nina Brenden; Stockholms universitet.; [1998]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Immunology; immunologi;

    Sammanfattning : .... LÄS MER