Sökning: "regulatory t cells"

Visar resultat 31 - 35 av 423 avhandlingar innehållade orden regulatory t cells.

1. 31. Infection induced chronic inflammation and it's association with prostate cancer initiation and progression

   Författare :Sabina Davidsson; Ove Andrén; Bo Söderquist; Jennifer Rider; Gisela Helenius; Jan-Erik Damber; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; chronic inflammation; CD4 helper T cells; CD8 cytotoxic T cells; regulatory T cells; Propionibacterium acnes; Medicine; Medicin;

   Sammanfattning : An association between cancer development and inflammation has long been suggested. Approximately 20% of all human cancers in adults are assumed to result from chronic inflammation. The aim of this thesis was to investigate if infection-induced chronic inflammation plays a role in prostate carcinogenesis. LÄS MER

3. 32. Regulatory T cells in type 1 diabetes: the role of IL-35 in counteracting the disease

   Författare :Kailash Singh; Thomas Mandrup-Poulsen; Uppsala universitet; []
   Nyckelord :IL-35; regulatory T cells; type 1 diabetes; LADA; kidney and diabetic nephropathy; Medicinsk vetenskap; Medical Science; Immunologi; Immunology; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

   Sammanfattning : Type 1 diabetes (T1D) is etiologically considered as an autoimmune disease, where insulin-producing β-cells are damaged by autoimmune attacks. Regulatory T (Treg) cells are immune homeostasis cells. In the present thesis I aimed to investigate the role of Treg cells and other immune cells in the early development of T1D. LÄS MER

4. 33. CD4+CD25+ T regulatory cells in multiple sclerosis

   Författare :Prabhakar Putheti; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Multiple sclerosis (MS) is a chronic, inflammatory, and demyelinating disease of the central nervous system (CNS), which is likely to be mediated by autoaggressive immunity. Treatments of MS that may beneficially influence the disease course consist of Avonex (interferon-beta; IFN-beta), and Copaxone (glatiramer acetate; GA). LÄS MER

5. 34. Mucosal T-cell and cytokine responses in Helicobacter pylori-infected duodenal ulcer patients

   Författare :Erika Strömberg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; mucosal immunology; antrum; duodenum; duodenal ulcer; asymptomatic; epithelial cells; cytokines; T cells;

   Sammanfattning : Helicobacter pylori colonizes the human stomach and areas of gastric metaplasia in the duodenum. The bacterium is the major cause of chronic active gastritis and peptic ulcer disease and is a risk factor for the development of gastric adenocarcinoma and lymphoma. LÄS MER

7. 35. Regulatory mechanisms controlling T cell activity

   Författare :Anette Sundstedt; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; T cell superantigen anergy interleukin-2 transcription factor cytotoxicity; serology; Immunology; Immunologi; serologi;

   Sammanfattning : This thesis is based on work studying the immunoregulatory mechanisms that govern the balance between activation and inactivation of T lymphocytes. Most of the work has been carried out in an experimental system using a T cell receptor (TCR-Vb3) transgenic mouse strain to obtain a homogenous T-cell population and utilizing the properties of bacterial superantigens to induce T cell responses and unresponsiveness in vivo. LÄS MER