Sökning: "regulatory region"

Visar resultat 1 - 5 av 266 avhandlingar innehållade orden regulatory region.

  1. 1. Regulatory mechanisms of amino acid-induced signaling in Saccharomyces cerevisiae

    Författare :Deike J. Omnus; Per O. Ljungdahl; Claudio De Virgilio; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Signal transduction; regulatory mechanisms; nutrient sensing; Saccharomyces cerevisiae; Cell Biology; cellbiologi;

    Sammanfattning : This thesis describes studies aimed at elucidating the molecular mechanisms that regulate the SPS (Ssy1-Ptr3-Ssy5) signal transduction pathway in the yeast Saccharomyces cerevisiae. This pathway is induced by extracellular amino acids and facilitates their uptake. LÄS MER

  3. 2. Genetic analysis of genes found on the 4th chromosome of Drosophila - emphasizing the developmental context of Pax6

    Författare :Jesper Kronhamn; Åsa Rasmuson-Lestander; Kevin Moses; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Pax6; twin of eyeless; headless flies; head development; eye development; eyeless; Minute; RpS3A; regulatory region; Drosophila; Genetik; Genetics; Genetik; Genetics; genetik;

    Sammanfattning : The small size and the lack of recombination set the fourth chromosome of Drosophila melanogaster apart from the other chromosomes. I have shown that the Minute gene on chromosome 4, earlier named Minute-4, encodes the ribosomal protein RpS3A. Two Pax6 genes, eyeless (ey) and twin of eyeless (toy) are also located on chromosome 4. LÄS MER

  4. 3. Regulatory T cells : molecular and clinical aspects

    Författare :Malin E Winerdal; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In the immune system’s tug of war with cancer, tolerance mechanisms by which the tumor can control anti-tumor immune responses play a central role in determining the outcome. Regulatory T cells (Treg) induced in the thymus or the periphery, represent one such tolerance mechanism that potentially can be exploited by developing tumors. LÄS MER

  5. 4. Studies on the Molecular Biology of the Mouse Pneumotropic Polyomavirus

    Författare :Shouting Zhang; Kristina Dörries; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; murine pneumotropic virus; Kilham mouse polyomavirus; large T antigen; enhancer; regulatory region rearrangement; gene expression regulation; DNA replication; transposable elements; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The Murine Pneumotropic Virus (MPtV), in contrast to the other MurinePolyomavirus (MPyV), appears to be non-tumourigenic in its natural host. Instead, MPtV causes acute pneumonia and can serve as a model in studies of polyomavirus-induced disease. In initial experiments, MPtV large T-antigen (LT) was expressed in a heterologous system. LÄS MER

  7. 5. Gene complexes and regulatory domains in metazoan genomes

    Författare :Pär Engström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite the recent massive increases in genome and transcript sequence data, including wholegenome sequences for humans and many other metazoans, our understanding of the content of these sequences is far from complete. This thesis is about making use of metazoan sequence data to detect functional genetic elements on a genome-wide scale and examine the distribution of those elements on chromosomes. LÄS MER