Sökning: "reference genes"
Visar resultat 1 - 5 av 124 avhandlingar innehållade orden reference genes.
1. Pancreatic Endocrine Tumourigenesis : Genes of potential importance
Sammanfattning : Understanding signalling pathways that control pancreatic endocrine tumour (PET) development and proliferation may reveal novel targets for therapeutic intervention. The pathogenesis for sporadic and hereditary PETs, apart from mutations of the MEN1 and VHL tumour suppressor genes, is still elusive. LÄS MER
2. Effects of Biomechanical Stress on Gene Regulation in Vascular Cells
Sammanfattning : The vascular vessel wall is constantly exposed to biomechanical forces, such as shear and tensile stress. Biomechanical forces are important for several physiological and pathological processes and have been shown to regulate a number of fundamental vascular functions, such as vascular tone and remodeling processes. LÄS MER
3. Development and Evaluation of Web Applications for Investigating Candidate Genes in Rat Models of Complex Diseases
Sammanfattning : Many human diseases, such as rheumatoid arthritis and type 2 diabetes mellitus, have a very complex development, depending on both environmental and multiple genetic factors. By crossing inbred rat strains susceptible to a genetic disorder with strains resistant to the same disorder, genomic regions associated with the disease can be identified, so called quantitative trait loci (QTLs). LÄS MER
4. DNA methylation in the placenta and in cancerwith special reference to folate transporting genes
Sammanfattning : DNA methylation is an epigenetic mechanism that regulates the gene transcription. Folate is used in cellular synthesis of methyl groups, nucleic acids and amino acids. In complex diseases like cancer and neural tube defects (NTD), various genetic and epigenetic alterations can be found that disrupt the normal cell function. LÄS MER
5. Phylogenetic Studies in the Euasterids II : with Particular Reference to Asterales and Escalloniaceae
Sammanfattning : The present study is concerned with the evolutionary relationships among the Euasterids II, a group of angiosperms that includes the orders Apiales, Aquifoliales, Asterales, and Dipsacales together with several small, poorly known families yet unplaced as to order.Parsimony analysis of nucleotide sequence data from the chloroplast genes atpB, ndhF and rbcL together with morphological data are used to construct a phylogeny of the order Asterals, which in the present sense includes 11 families and more than 26 000 species. LÄS MER