Sökning: "reference gene"

Visar resultat 21 - 25 av 172 avhandlingar innehållade orden reference gene.

1. 21. Familial risks for cancer with reference to lung cancer

   Författare :Xinjun Li; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Familial cancer; population-based; hereditary factors; familial risk; lung neoplasms.;

   Sammanfattning : Familial aggregation of cancer may be due either to environmental factors shared by family members, or to shared genes. Familial clustering has been an avenue to the understanding of the etiology of cancer and has been a basis for clinical decisions and counseling, as well as guiding the identification of cancer-related genes. LÄS MER

3. 22. The art of transcriptome reconstruction : with applications in Picea abies (L.) H. Karst

   Författare :Karl Johan Westrin; Olof Emanuelsson; Henric Zazzi; Lukas Käll; Jens Sundström; Jarkko Salojärvi; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; transcriptome reconstruction; transcriptome assembly; transcript isoform detection; Picea abies; acrocona; cone setting; differential expression; gene families; miRNA; quality assessment; transkriptomrekonstruktion; sammansättning av transkriptom; detektering av transkriptisoform; rödgran; kottegran; kottsättning; differentiellt uttryck; genfamiljer; kvalitetsutvärdering; miRNA; Biotechnology; Bioteknologi;

   Sammanfattning : Transcriptome reconstruction is an important component in the bioinformatical part of transcriptome studies. When a reference genome is missing, highly fragmented or incomplete, a de novo transcriptome assembly is the transcriptome reconstruction approach of choice, since in such situations, a simple alignment (or mapping) would not necessarily give all theinformation concerning splice junctions, isoforms or even the full extent of the gene. LÄS MER

4. 23. The Genetics of Speciation and Colouration in Carrion and Hooded Crows

   Författare :Jelmer Poelstra; Jochen Wolf; Hans Ellegren; Chris Jiggins; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; evolutionary genetics; genomics; birds; next-generation sequencing; pigmentation; pigmentation genetics; eumelanin; social selection; gene expression; population genomics; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

   Sammanfattning : A fundamental goal in biological research is to gain an understanding of the evolutionary processes and genetic elements that drive speciation. Genes responsible for reproductive isolation in young divergent lineages are particularly poorly known. In this thesis, the speciation genetics of carrion (Corvus (corone) corone) and hooded (C. LÄS MER

5. 24. High-resolution Studies of mRNA Expression in Brain : A Search for Genes Differently Expressed in Schizophrenia

   Författare :Anja Castensson; Elena Jazin; Terence Speed; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; mRNA; gene expression; real-time RT-PCR; schizophrenia; 5-HT serotonin receptor 2C; brain; psychiatric genetics; Genetik; Clinical genetics; Klinisk genetik;

   Sammanfattning : Gene expression differences between patients and controls can be used to find susceptibility genes and drug targets for a disease. High-resolution strategies are required because the differences between the investigated groups may be small and numerous factors may affect the mRNA quantity. LÄS MER

7. 25. DNA methylation and gene expression patterns in adrenal medullary tumors

   Författare :Nimrod G B Kiss; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Pheochromocytomas and abdominal paragangliomas are neuroendocrine tumors of the autonomous nervous system, arising in adrenal medulla and sympathetic ganglia throughout the abdomen. These tumors originate from catecholamine-producing chromaffin cells. Neuroblastomas are common childhood tumors in the adrenal medulla and abdominal ganglia. LÄS MER