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Visar resultat 1 - 5 av 17 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Gut Mucosal Reactivity to Gluten and Cow´s Milk Protein in Rheumatic Diseases

   Författare :Maria Lidén; Roger Hällgren; Gudjón Kristjánsson; Sigrídur Valtýsdóttir; Thomas Skogh; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Primary Sjögren’s syndrome; rheumatoid arthritis; spondyloarthropathies; rectal challenge; food sensitivity; myeloperoxidase; nitric oxide and barrier permeability; Rheumatology; Reumatologi; Medicine; medicin;

   Sammanfattning : This thesis comprised patients with chronic rheumatic diseases. The studies aimed to elucidate food sensitivity by measuring mucosal inflammatory reactivity and thereby a possible link between the gut and joints. LÄS MER

3. 2. Rectal cancer : staging, radiotherapy and surgery

   Författare :Anna Martling; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Rectal cancer; surgery; radiotherapy; staging; prognosis;

   Sammanfattning : In Sweden, about 1800 patients are annually diagnosed with adenocarcinoma of the rectum. Surgery remains the major primary treatment. Adjuvant radiotherapy and total mesorectal excision (TME) are two major achievements in rectal cancer treatment during the last two decades. LÄS MER

4. 3. Locally advanced rectal cancer : aspects on management, outcome and quality of life

   Författare :Gabriella Jansson Palmer; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Locally recurrent rectal cancer; locally advanced primary rectal cancer; survival; radiological staging; MDT;

   Sammanfattning : Rectal cancer is common in Sweden, with about 1650 patients diagnosed annually. In 10-15% of the patients the tumour is locally advanced at diagnosis, i.e. the cancer is growing outside the mesorectal fascia, into adjacent organs in the pelvis. LÄS MER

5. 4. Food Antigen Sensitivity in Coeliac Disease Assessed by the Mucosal Patch Technique

   Författare :Guðjón Kristjánsson; Roger Hällgren; Per Venge; Riccardo Troncone; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Coeliac disease; Diagnostic instrument; food hypersensitivity; gut pathophysiologi; inflammation; nitric oxide; rectal instillation; gluten; corn; milk hypersensitivity; inflammatory bowel disease; irritable bowel syndrome; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Sammanfattning : A diagnosis of coeliac disease (CD) in adults relies on the presence of a structurally abnormal intestinal mucosa, followed by a clear clinical remission on a gluten-free diet. There is a clear need for a rapid, simple, safe and sensitive method to determine the type and intensity of inflammation in the gut mucosa in clinical practice. LÄS MER

7. 5. Immune Cell Profiling of Colorectal Cancers: Unravelling the Connection to Treatment Responses

   Författare :Azar Rezapour; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rectal cancer; Tumor infiltrating T cell; MxA; Interferon type I; CD39; CD103; PD-1; cytokines; response to the treatment;

   Sammanfattning : Understanding the interplay between tumor cells and the immune system holds the key to the development of more effective treatments for cancer patients. Therefore, we have emphasized our efforts on deciphering the intricacies of these interactions to pave for more effective therapeutic strategies. LÄS MER