Sökning: "recombinant technology"

Visar resultat 1 - 5 av 155 avhandlingar innehållade orden recombinant technology.

  1. 1. Mucin-like fusion proteins produced in Pichia pastoris as enhancers of immunogenecity of recombinant vaccines

    Författare :Magnus Sjöblom; Sven-Olof Enfors; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biokemisk processteknik; Biochemical Process Engineering;

    Sammanfattning : .... LÄS MER

  3. 2. Gene technology at stake : Swedish governmental commissions on the border of science and politics

    Författare :Jenny Eklöf; Kjell Jonsson; Christer Nordlund; Susanne Lundin; Umeå universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Gene technology; biotechnology; recombinant DNA technology; bioethics; ethics; risk; GMO; embryo; transgenic organisms; boundary organization; boundary object; governmental commission; regulatory policy; Sweden; public; expertise; democracy; History of science and ideas; Idé- o lärdomshistoria;

    Sammanfattning : This thesis examines the Swedish political response to the challenges posed by gene technology, seen through the prism of governmental commissions. It discerns and analyses continuities and changes in the Swedish political conception of gene technology, over the course of two decades, 1980–2000. LÄS MER

  4. 3. Tools for the development of intensified perfusion processes for mammalian cell culture

    Författare :Hubert Schwarz; Véronique Chotteau; Mark Smales; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Recombinant protein biomanufacturing; Perfusion process; Integrated continuous bioprocessing; Monoclonal antibody; Erythropoietin; Chinese Hamster Ovary cells; Human Embryonic Kidney cells; Perfusion medium optimization; Cell specific perfusion rate; Raman spectroscopy; N-glycosylation; Microbioreactors; Design of Experiments; Biotechnology; Bioteknologi;

    Sammanfattning : Recombinant protein therapeutics have become an indispensable part of modern medicine to treat a wide variety of diseases. Their manufacture is mostly based on mammalian cells with fed-batch production bioreactors and downstream batch purification unit operations. LÄS MER

  5. 4. Influence of recombinant passenger properties and process conditions on surface expression using the AIDA-I autotransporter

    Författare :Martin Gustavsson; Gen Larsson; Peter Neubauer; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; AIDA-I; Autotransport; Biocatalysis; Escherichia coli; Live vaccines; Surface expression;

    Sammanfattning : Surface expression has attracted much recent interest, and it has been suggested for a variety of applications. Two such applications are whole-cell biocatalysis and the creation of live vaccines. LÄS MER

  7. 5. Pichia pastoris as a platform for the production of therapeutic glycoproteins

    Författare :Magnus Sjöblom; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biokemisk processteknik; Biochemical Process Engineering;

    Sammanfattning : Recombinant protein therapeutics is a growing market within the human medical biotechnology industry. The majority of all approved biopharmaceuticals are protein based and includes for example blood factors, anticoagulants, hormones, vaccine and monoclonal antibodies. LÄS MER