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Visar resultat 21 - 25 av 374 avhandlingar som matchar ovanstående sökkriterier.

  1. 21. Immunodominant proteins in Giardia lamblia

    Författare :Malin Weiland; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The protozoan parasite Giardia lamblia is a major cause of diarrhoea in humans and other mammals. Infection starts by ingestion of infectious cysts that excyst in the upper part of the small intestine and attach to intestinal epithelial cells. LÄS MER

  3. 22. Anticoagulant protein C--structural and functional studies

    Författare :Lei Shen; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enzymology; Proteins; Klinisk kemi; Clinical chemistry; serpins; membrane binding; factor V; protein C; protein S; Proteiner; enzymologi;

    Sammanfattning : Anticoagulant protein C is a vitamin K-dependent factor circulating in plasma as a zymogen of a serine protease. It is converted to its active form (APC) by the thrombin-thrombomodulin complex on the surface of endothelial cells. APC inhibits the generation of thrombin by selective proteolytic inactivation procoagulant factors Va and VIIIa. LÄS MER

  4. 23. Alphavirus vectors as recombinant vaccines

    Författare :Peter Berglund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Semliki Forest virus; Alphavirus; Synthetic vaccmes; Influenza A virus; HIV-I; SIV; DNA vaccines; AIDS vaccines; Influenza vaccine;

    Sammanfattning : This thesis describes further developments of an expression system based on the alphavirus Semliki Forest virus (SFV), and its potential use as recombinant vaccine. The RNA genome of SFV contains a 3'open reading frame (ORF) encoding the structural proteins, and a 5' ORF coding for the viral replicase. LÄS MER

  5. 24. Recombinant Enzymes in Pyrosequencing Technology

    Författare :Nader Nourizad; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; apyrase; pyrosequencing; pichia pastoris; protein expression; fusion protein; luciferase; DNA template; clone checking; DNA polymerase;

    Sammanfattning : Pyrosequencing is a DNA sequencing method based on thedetection of released pyrophosphate (PPi) during DNA synthesis.In a cascade of enzymatic reactions, visible light isgenerated, which is proportional to the number of nucleotidesincorporated into the DNA template. When dNTP(s) areincorporated into the DNA template, inorganic PPi is released. LÄS MER

  7. 25. Immunoreactive proteins in Taenia solium

    Författare :Fernando Salazar-Anton; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Taenia solium cysticercosis is a neglected zoonotic disease that constitutes a serious public health problem in many low-income countries of Latin America, Africa, and Asia. Although diagnostic antigens are available, it is still necessary to identify new targets to improve the current diagnostic methods. LÄS MER