Sökning: "recombinant allergen"

Visar resultat 16 - 20 av 23 avhandlingar innehållade orden recombinant allergen.

  1. 16. Targeting the IL-33/ST2 pathway in asthma : implications for development, exacerbation and treatment

    Författare :Anna Zoltowska Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Asthma is a term that encompasses a disease spectrum with different phenotypes that vary in severity and whose common characteristic is airflow limitation. Allergic asthma is the most common phenotype of asthma and is characterized by allergen induced inflammatory responses, airway hyperresponsiveness (AHR), and remodeling. LÄS MER

  3. 17. Cat allergy : diagnosis and characterization of important allergens

    Författare :Justus Adédoyin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Allergy affects about 25% of the population. Allergic diseases are manifested in many ways, from mild rhinitis to life-threatening anaphylaxis. Globally, more than 15% of children and adults are allergic to pets. The focus of this thesis is important cat allergens. LÄS MER

  4. 18. Interleukin-17 in models of neutrophilic lung disease

    Författare :Stefan Ivanov; Göteborgs universitet; []
    Nyckelord :Interleukin-17; Interleukin-23; Matrix metalloproteinase-9; neutrophils; macrophages; CD4 cells; innate response; lungs;

    Sammanfattning : Several acute or chronic lung disorders like adult respiratory distress syndrome, acute severe asthma, chronic obstructive pulmonary disease, chronic lung allograft rejection and cystic fibrosis, are associated with signs of an excess innate response in the bronchoalveolar space. Neutrophils may play a pathogenic role in these lung diseases by contributing to non-specific bronchial hyperresponsiveness and bronchial hypersecretion, as well as to epithelial damage and tissue remodelling. LÄS MER

  5. 19. The role of Malassezia allergens and mast cells in atopic eczema

    Författare :Christine Selander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atopic eczema (AE) is a chronic inflammatory skin disease, characterized by intense itching, dry skin, infiltration of immune cells and skin lesions. To date, the cause of AE, a disease affecting 15-30% of children and 2-10% of adults, remains unknown and the pathomechanisms are not fully understood. LÄS MER

  7. 20. Mechanism and therapy of hereditary angioedema typ III and role of the contact system in inflammatory diseases

    Författare :Jenny Björkqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Combinations of proinflammatory and procoagulant reactions are associated with a variety of disorders affecting the cardiovascular system. Vascular leakage contributes to the pathology of conditions such as, sepsis, allergy and anaphylactic reactions. LÄS MER