Sökning: "receptor"
Visar resultat 21 - 25 av 4114 avhandlingar innehållade ordet receptor.
21. The prostanoid FP receptor and uveoscleral outflow : A study of FP receptor expression and functions in the eye
Sammanfattning : Prostaglandin F2α is a prostanoid FP receptor agonist which acts as an intraocular pressure-lowering agent by increasing the uveoscleral outflow of aqueous humour through the ciliary muscle. The aim of this, thesis was to investigate possible mechanisms of the increased uveoscleral outflow induced by prostaglandin F2α and its analogue latanoprost acid. LÄS MER
22. Functional characterisation of the CAG polymorphism in the androgen receptor- in vitro and in vivo
Sammanfattning : The androgen receptor (AR) is the mediator of androgen actions. In the AR coding region there is a polymorphic CAG repeat encoding a stretch of the amino acid glutamine (Q). The repeat length modulates receptor activity and is normally distributed between 10-30 CAG with a median length of 22 repeats in white men. LÄS MER
23. Polymorphism in sex steroid-related genes. Effects on hormone levels and behavior
Sammanfattning : Genetic factors are important for variations between individuals with respect to most humantraits and diseases. Sex steroids are of profound importance for reproduction, metabolism,cardiovascular function and bone formation. They are potent regulators of their ownsynthesis as well as of that of other hormones, including prolactin. LÄS MER
24. Tissue tropism and oncolytic potential of enteroviruses
Sammanfattning : .... LÄS MER
25. Neuropeptide Y - aspects of vasomotorresponses and receptor characterization
Sammanfattning : Abstract The aims of the present thesis were to examine neuropeptide Y (NPY) responses in different human and guinea pig vascular beds and in cultured human vascular smooth muscle cells (VSMC) and to characterize, with different NPY agonists and the specific NPY Y1 receptor antagonist (BIBP3226), the NPY receptors involved. NPY-induced strong and potent contractions in human cerebral and subcutaneous arteries and in guinea pig basilar arteries. LÄS MER