Sökning: "receptor trafficking"
Visar resultat 6 - 10 av 74 avhandlingar innehållade orden receptor trafficking.
6. T-Cell Protein Tyrosine Phosphatase, a Regulator of the PDGF Signaling Pathway
Sammanfattning : Platelet-derived growth factor (PDGF) is a potent stimulator of cell growth, survival and motility. PDGF exerts its function by binding to specific tyrosine kinase receptors, initiating receptor auotphosphorylation and initiation of specific signaling pathways that regulates the cellular response. LÄS MER
7. Exploring Cellular Dynamics : From Vesicle Tethering to Cell Migration
Sammanfattning : Cells in the body communicate with each other in order to cooperate efficiently. This communication is in part achieved by regulated secretion of signaling molecules, which when released from a cell may activate receptors present at the plasma membrane of an adjacent cell. Such signals affect both cell fate and behavior. LÄS MER
8. Novel roles of ErbB3 receptor tyrosine kinase in vesicular trafficking
Sammanfattning : ErbB3 is a catalytically impaired receptor tyrosine kinase (RTK) from the EGFR family. Upon ligand binding, ErbB3 forms heterodimers with other members of the family and triggers phosphorylation cascades that promote crucial cellular functions as proliferation, differentiation and survival. LÄS MER
9. Organization of signaling networks during receptor-mediated membrane protein trafficking
Sammanfattning : The mechanisms by which receptor signals are organized in a synergic/hierarchical manner in time and space during regulation of integral membrane protein traffic remain a present challenge. The aim of this study was to address some critical aspects of these processes. LÄS MER
10. Role of macrophage receptor MARCO in host defense
Sammanfattning : Innate immunity, the first line of defense against infectious microorganisms, appeared early in evolution. Innate immunity relies on specialized cells such as macrophages that are the first to encounter pathogens during infection. LÄS MER