Sökning: "receptor antagonism"

Visar resultat 16 - 20 av 59 avhandlingar innehållade orden receptor antagonism.

  1. 16. Effects of Free Fatty Acids on Insulin and Glucagon Secretion : – with special emphasis on the role of Free fatty acid receptor 1

    Författare :Hjalti Kristinsson; Peter Professor; Birgitte Holst; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FFAR1; GPR40; palmitate; lipotoxicity; islets of Langerhans; type 2 diabetes; obesity; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Prevalence of type 2 diabetes mellitus (T2DM) is still rising and even so in the juvenile population. Obesity is highly associated with increased risk for developing T2DM. LÄS MER

  3. 17. Signal transduction via estrogen receptors (ERs) and estrogen receptor-related receptors (ERRs)

    Författare :Katarina Pettersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogens influence post-natal development and function of the female reproductive system and other organs including bone and cardiovascular system. Estrogens are also involved in the development and growth of certain cancers in e.g. breast and uterine endometrium. LÄS MER

  4. 18. OXYTOCIN AND VASOPRESSIN IN UTERINE ACTIVITY. Receptor-mediated agonism and antagonism with special regard to the aetiology and treatment of preterm labour and primary dysmenorrhoea

    Författare :Thomas Bossmar; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; primary dysmenorrhoea.; preterm labour; vasopressin antagonist; receptors; oxytocin antagonist; vasopressin; Oxytocin; gynaecology; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Sammanfattning : With a view to the aetiology and treatment of preterm labour and primary dysmenorrhoea we studied the influence of sexual steroids on the plasma levels of oxytocin and vasopressin, effect of these peptides on uterine contractility in vitro and in vivo, receptor concentrations and antagonists to oxytocin and vasopressin. In postmenopausal women oestrogen increased the concentrations in plasma of both peptides, whereas progesterone increased oxytocin but decreased vasopressin levels. LÄS MER

  5. 19. Renal failure in experimental sepsis : role of endothelin and the toll-like receptor 4

    Författare :Johan Fenhammar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Sepsis is the leading cause of renal failure in critically ill patients, but the pathogenesis of septic kidney dysfunction is poorly defined. The current paradigm states that hypoperfusion and excessive renal vasoconstriction results in renal ischemia. LÄS MER

  7. 20. The Gastrin-ECL Cell Axis. Functional Aspects

    Författare :Maria Björkqvist; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; Pharmacological sciences; Calcium channels; CCK receptor antagonists; Misoprostol; Galanin; Somatostatin; Pancreastatin; Histamine; VIP; Gastrin; PACAP;

    Sammanfattning : The ECL cells constitute a prominent endocrine cell population in the acid-producing part of the stomach. They are controlled by circulating gastrin released from G-cells in the antrum. In response to gastrin, they secrete histamine, that in turn stimulates the parietal cell to secrete acid. LÄS MER