Sökning: "real-world evidence"
Visar resultat 1 - 5 av 56 avhandlingar innehållade orden real-world evidence.
1. Lifestyle Intervention from a Health Economics Perspective
Sammanfattning : Abstract The aim of this thesis was to perform health economic analyses of lifestyle intervention for people at a high risk of cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM). The results can help decision-makers to make informed decisions over implementing lifestyle intervention, taking several dilemmas into consideration. LÄS MER
2. Real-world outcomes in oncology : assessing the value of rewardable innovation
Sammanfattning : Recent years have seen a remarkable expansion of therapeutic options available for many forms of cancer. Evidence for the efficacy of these treatments have mainly come from randomized controlled trials, however questions often remain regarding the actual use, effectiveness and value of innovative therapies when used under the circumstances of routine clinical practice. LÄS MER
3. Benefits and harms of Bisphosphonates : an observational study
Sammanfattning : Background: Bisphosphonates are first-line treatment for osteoporosis, but osteoporosis is considered an undertreated disease. The general aim of this dissertation was to further study the benefits and harms of bisphosphonates. LÄS MER
4. Investigating the treatment of metastatic breast cancer : real-world evidence on treatment patterns, safety and efficacy
Sammanfattning : Metastatic breast cancer is an incurable disease causing a spectrum of symptoms and leading to a continuous deterioration of performance status and quality of life. It is a heterogeneous disease, with survival being related to tumor biology and patient-related factors. LÄS MER
5. Population-based studies in Myelodysplastic syndromes : Prognostic scores, socioeconomic status, and therapy-related disease
Sammanfattning : The aim of this thesis was to expand the epidemiological knowledge of the haematological malignancy MDS and the related condition chronic myelomonocytic leukaemia (CMML). Using nationwide registers, the papers in this thesis address aspects of prognostication, comorbidity, socioeconomic status, and therapy-related disease, using a population-based approach. LÄS MER