Sökning: "real options"

Visar resultat 21 - 25 av 110 avhandlingar innehållade orden real options.

  1. 21. Real-world outcomes in oncology : assessing the value of rewardable innovation

    Författare :Nahila Justo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Recent years have seen a remarkable expansion of therapeutic options available for many forms of cancer. Evidence for the efficacy of these treatments have mainly come from randomized controlled trials, however questions often remain regarding the actual use, effectiveness and value of innovative therapies when used under the circumstances of routine clinical practice. LÄS MER

  3. 22. Robust industrial automation software: outsets for non-determinism and real-time execution

    Författare :Marcus Lindner; Alois Zoitl; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Inbyggda system; Embedded Systems;

    Sammanfattning : Studies about the industrial standard IEC 61499 and its relation to the RTFM Model of Computation represent the basis of this thesis. An overview of industrial automation software in general and in the scope of Svenska Kraftnät introduces the subject of software related issues. LÄS MER

  4. 23. Improving chemotherapy in advanced urothelial cancer : real-world data studies and prospective clinical trials

    Författare :Karin Holmsten; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Advanced urothelial cancer (UC) is an aggressive disease with high morbidity and mortality. The primary aim of this thesis was to improve chemotherapy with respect to treatment efficacy, safety, and health-related quality of life (HRQoL) in advanced UC. LÄS MER

  5. 24. Angiogenesis in human renal cell carcinoma : hypoxia, vascularity and prognosis

    Författare :Johanna Sandlund; Torgny Rasmuson; Börje Ljungberg; Kjell Grankvist; Anders Bergh; Elisabeth Kjellén; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endoglin CD105; CD31; prognosis; CA IX; HIF-2α; renal cell carcinoma; tissue microarray; immunohistochemistry; real-time PCR; stage; grade; Oncology; Onkologi;

    Sammanfattning : Background: Angiogenesis is recognised as a critical step in tumour progression. The angiogenic switch is activated by various trigger signals, such as hypoxia, low pH, and genetic mutations. Renal cell carcinoma (RCC) is often an aggressive tumour, and advanced disease has limited treatment options and bad prognosis. LÄS MER

  7. 25. The pragmatic randomised trial : a simple research design for real-world evaluation of innovation in tuberculosis care

    Författare :Merrick Zwarenstein; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tuberculosis was the first disease in history whose treatment regimens were systematically established using randomised controlled trials (RCTs). As a result TB drug treatment regimens are standardised globally, and have been entirely evidence-based for decades. LÄS MER