Sökning: "reactive oxygen species"

Visar resultat 21 - 25 av 383 avhandlingar innehållade orden reactive oxygen species.

  1. 21. Targeting NOX2 in cancer

    Författare :Ebru Aydin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; reactive oxygen species; immunotherapy; nox2; nk cells; melanoma; histamine; metastasis; leukemia; aml; cml; kras; mpd;

    Sammanfattning : Reactive oxygen species (ROS) are short-lived, toxic derivatives of oxygen that are produced during mitochondrial respiration and by NADPH oxidases (NOX). By enzymatically generating ROS, the myeloid cell NOX2 plays a critical role in defense against bacteria and other microorganisms. LÄS MER

  3. 22. Antibacterial Strategies for Titanium Biomaterials

    Författare :Erik Unosson; Ken Welch; Håkan Engqvist; Timo Närhi; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Titanium; silver; biomaterial; antibacterial; photocatalysis; hydrogen peroxide; reactive oxygen species; combinatorial materials science; Engineering Science with specialization in Materials Science; Teknisk fysik med inriktning mot materialvetenskap;

    Sammanfattning : Titanium and titanium based alloys are widely used in dentistry and orthopedics to replace hard tissue and to mend broken bones. It has become a material of choice due to its low density, high strength, good biocompatibility and its capacity to integrate closely with the bone. LÄS MER

  4. 23. Redox reactions in cancer: impact and regulation

    Författare :Hanna Grauers Wiktorin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Immunotherapy; reactive oxygen species; NOX2; histamine dihydrochloride; myeloid-derived suppressor cells; checkpoint inhibition; acute myeloid leukemia; chronic myeloid leukemia;

    Sammanfattning : The reduction-oxidation (redox) reaction involves a change in the oxidation state of molecules where a molecule that donates an electron is oxidized and a molecule that accepts an electron is reduced. The NADPH oxidase of myeloid cells, NOX2, is a major source of oxidants in the form of reactive oxygen species (ROS), which are short-lived oxygen derivatives. LÄS MER

  5. 24. Titanium Dioxide Photocatalysis in Biomaterials Applications

    Författare :Yanling Cai; Ken Welch; Maria Strømme; Håkan Engqvist; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; titanium dioxide; photocatalysis; bioactivity; antibacterial effect; metabolic activity assay; biofilm; reactive oxygen species; disinfection kinetics; post-UV;

    Sammanfattning : Despite extensive preventative efforts, the problem of controlling infections associated with biomedical materials persists. Bacteria tend to colonize on biocompatible materials and form biofilms; thus, novel biomaterials with antibacterial properties are of great interest. LÄS MER

  7. 25. Therapeutic opportunities of alpha-1-microglobulin A study in placenta, blood, skin and eye

    Författare :Martin Cederlund; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reactive oxygen species; hemoglobin; myeloperoxidase; oxidative stress; α1-microglobulin;

    Sammanfattning : This thesis describes functional studies of the human protein alpha-1-microglobulin (A1M), with the aim of exploring its usefulness as a therapeutic agent in diseases where oxidative stress is a prominent feature. A1M is a 26 kDa plasma and tissue protein with reductase activity and radical- and heme-binding antioxidative functions. LÄS MER