Sökning: "reactive astrocytes"

Visar resultat 16 - 20 av 47 avhandlingar innehållade orden reactive astrocytes.

1. 16. Astrocytes during HIV infection of the brain : relevance for neuropathogenesis

   Författare :Farideh Sabri; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The overall aim of the present thesis was to characterize the role that astrocytes play for neuropathogenesis of AIDS dementia complex (ADC). We studied whether it is possible to derive the phenotype of HIV-1 virus by analyzing V3 sequences. LÄS MER

3. 17. Inflammation and Cell Profileration Following Perinatal Brain Injury

   Författare :Katarina Järlestedt; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hypoxia-ischemia; immature brain; reactive gliosis; complement system; C3a; fear conditioning; lipopolysaccharide; inflammation;

   Sammanfattning : Inflammation plays an important role in cerebral ischemic injury in the immature brain. The aim of the thesis was to investigate (1) the role of astrocyte activation and reactive gliosis in neonatal hypoxic-ischemic (HI) brain injury, (2) the role of complement derived peptide C3a in neonatal HI brain injury, (3) the effect of neonatal HI brain injury on fear learning and behaviour, (4) the effects of lipopolysaccharide (LPS) induced systemic inflammation on cell proliferation in the developing brain. LÄS MER

4. 18. In vivo responses of neural progenitor cells to extracellular matrix signaling under pathological conditions

   Författare :Reza Motalleb; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptide Amphiphiles; Biomaterial; Tenascin - C; RGDS; RHAMM; Reactive Gliosis; Rostral Migratory Stream; Extracellular Matrix;

   Sammanfattning : The adult brain has an inherently low capacity for tissue regeneration, and neurons lost to disease or injuries are normally not replaced. This becomes especially apparent when stroke or brain trauma occurs. The discovery of neurogenesis and neural stem cells in the adult brain has opened up new avenues for treatment of the injured brain. LÄS MER

5. 19. The interaction between astrocytes and excitatory synapses in health and disease

   Författare :Ipsit Srivastava; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Synaptic transmission forms the basis of neuronal activity and astrocytes play an integral part in this process. Glutamate is the major excitatory neurotransmitter in the brain and an important function of astrocyte during excitatory synaptic activity involves the uptake of glutamate through astrocyte glutamate transporters (EAATs) and hence shaping the excitatory neurotransmission. LÄS MER

7. 20. On the importance of inflammation for personality traits and psychiatric morbidity

   Författare :Petra Suchankova; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; C-reactive protein; complement factor H; S100B; receptor for advanced glycation end products; polymorphism; gene expression; personality traits; suicidal behaviour; schizophrenia; depression; Flinders sensitive line;

   Sammanfattning : Background: Pro-inflammatory mediators have been implicated in processes that could be both beneficial and toxic to cells in the brain. On the one hand balanced levels of these mediators favour e.g. LÄS MER