Sökning: "rat wistar"
Visar resultat 1 - 5 av 42 avhandlingar innehållade orden rat wistar.
1. About hyaluronan in the hypertrophic heart : studies on coordinated regulation of extracellular matrix signalling
Sammanfattning : Background. Myocardial hypertrophy is a risk factor for cardiovascular morbidity and mortality. Independent of underlying disease, the cardiac muscle strives in different ways to compensate for an increased workload. This remodelling of the heart includes changes in the extracellular matrix which will affect systolic and diastolic cardiac function. LÄS MER
2. Diabetic osteopathy : a study in the rat
Sammanfattning : The present study on non-obese Goto-Kakizaki (GK) rats with type-2 diabetes and neuropathy was an attempt to describe and define pertinent features of diabetic osteopathy. Altogether, the study included 33 GK rats aged 12 and 20 months, and 36 age-matched Wistar rats as controls. LÄS MER
3. Behavioral effects of female sex steroid hormones : models of PMS and PMDD in Wistar rats
Sammanfattning : Background Animal models can be used to mimic human conditions of psychopathology, and also as pre-clinical models to evaluate candidate drugs. With hormonal treatment it is possible to produce behavior in the rat which corresponds to the mental symptoms of pre-menstrual syndrome (PMS), and pre-menstrual dysphoric disorder (PMDD). LÄS MER
4. Mechanisms of opiate tolerance and dependence in the rat
Sammanfattning : Drug addiction is a complex phenomenon with various biological, psychological and social causes and consequences, which belongs to the major problems of today's society. Opiates have been used and misused for thousand of years and addiction to them develops both in humans and in animals. LÄS MER
5. On the possible role of serotonin and angiotensin for the respiratory abnormalities observed in panic disorder and premenstrual dysphoria
Sammanfattning : Panic disorder and premenstrual dysphoria are accompanied by intriguing abnormalities related to the control of respiration, including enhanced responsiveness to CO2 and enhanced respiratory variability. These aberrations do not seem to be shared by other psychiatric disorders, but appear to be relatively unique for panic disorder and premenstrual dysphoria. LÄS MER