Sökning: "rapid cognitive decline"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden rapid cognitive decline.

  1. 1. Lexical and articulatory aspects of cognitive decline

    Författare :Per Östberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Dementia may be defined as the attenuation of cognitive powers despite preserved basal consciousness. Its most common cause is Alzheimer's disease (AD). Pathoanatomical staging has made it clear that the disease passes through a protracted preclinical phase with slowly emerging symptoms. LÄS MER

  3. 2. Biomarkers as Monitors of Drug Effect, Diagnostic Tools and Predictors of Deterioration Rate in Alzheimer’s Disease

    Författare :Malin Degerman Gunnarsson; Lena Kilander; Hans Basun; Jan Marcusson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; biomarkers; CSF; PIB PET; amyloid-beta; tau; rapid cognitive decline; dying in severe dementia; mortality; neuropsychological tests; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Decreased amyloid-ß42 (Aß42), increased total tau (t-tau) and phosphorylated tau (p-tau) in cerebrospinal fluid (CSF) reflect histopathological core changes in the most common dementia disorder, Alzheimer’s disease (AD). They discriminate AD from healthy controls and predict conversion to AD with a relatively high accuracy. LÄS MER

  4. 3. Brain characteristics of memory decline and stability in aging : Contributions from longitudinal observations

    Författare :Sara Pudas; Jonas Persson; Lars Nyberg; Emrah Düzel; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; aging; episodic memory; individual differences; longitudinal assessment; magnetic resonance imaging; hippocampus; frontal cortex; Psychology; psykologi;

    Sammanfattning : Aging is typically associated with declining mental abilities, most prominent for some forms of memory. There are, however, large inter-individual differences within the older population. Some people experience rapid decline whereas others seem almost spared from any adverse effects of aging. LÄS MER

  5. 4. Old age depression : occurrence and influence on cognitive functioning in aging and Alzheimer's disease

    Författare :Anna-Karin Berger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The general aims of this thesis were to examine the occurrence of depressive symptoms three years before the diagnoses of depression and Alzheimer's disease (AD), and to study the effects of depression on cognitive functioning in aging and AD. Five empirical studies were conducted. LÄS MER

  7. 5. Effects of Indigestible Carbohydrates and GI of Cereal Products on Glucose Metabolism, Satiety and Cognitive Function in Healthy Subjects; Emphasising mechanisms for glycaemic regulation at the acute, second and third meal

    Författare :Anne Nilsson; Avdelningen för livsmedel och läkemedel; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Näringslära; colonic fermentation; indigestible carbohydrates; Nutrition; glycaemia and cognitive functions glycaemia; second-meal effect; insulin resistance; Glycaemic index; Glucose metabolism;

    Sammanfattning : The metabolic syndrome includes a cluster of dysfunctions that identifies subjects at high risk of developing type 2 diabetes and cardiovascular disease. The prevalence of the metabolic syndrome has increased markedly over the last two decades. Central to this syndrome is insulin resistance and hyperglycaemia, but also other manifestations, e.g. LÄS MER