Sökning: "randomization"

Visar resultat 11 - 15 av 130 avhandlingar innehållade ordet randomization.

1. 11. Genetic factors affecting pregnancy duration in humans

   Författare :Jonas Bacelis; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; genomics; GWAS; Mendelian randomization; causal inference; preterm birth; pregnancy; gestation; height; text mining;

   Sammanfattning : This thesis investigates the mechanisms behind human pregnancy duration. Too short gestation is a direct cause of perinatal, neonatal, and infant mortality. Deviation from normal pregnancy length is also associated with a child's morbidity, even in the adulthood. LÄS MER

3. 12. Optimizing Exposome-wide Assessments in Cardiometabolic Risk

   Författare :Hugo Pomares-Millan; Genetisk och molekylär epidemiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lifestyle; Nutritional epidemiology; Cardiometabolic risk; Prediabetes; cardiovascular disease CVD ; Type 2 diabetes T2D ; Machine learning; causal inference; Mediation analysis; Mendelian randomization;

   Sammanfattning : This thesis is focused on cardiovascular disease (CVD) and type 2 diabetes mellitus (T2D), two concomitant conditions that appear with growing concern. In our work, we aim to improve the identification of individuals at-risk of cardiometabolic disease through the characterization of complex environmental exposures (i.e. LÄS MER

4. 13. Essays on the Evaluation of Public Policies

   Författare :Michihito Ando; Matz Dahlberg; Che-Yuan Liang; David Neumark; Uppsala universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Local income growth; Local employment; Nuclear power facilities; Synthetic control method; Quantitative case study; Regression kink design; Endogenous treatment; Intergovernmental grants; Flypaper effect; Treatment effect heterogeneity; Instrumental variable; Oral health; Dentures; Price elasticity; Regression discontinuity design; Cost sharing; Randomization test; Economics; Nationalekonomi;

   Sammanfattning : This thesis consists of four self-contained papers.Essay 1: This paper uses the synthetic control (SC) method to examine how the establishment of Nuclear Power Facilities (NPFs) in Japan in the 1970s and 1980s has affected local per capita income levels in the municipalities in which they were located (NPF municipalities). LÄS MER

5. 14. Understanding the genetic architecture of fatty liver disease

   Författare :Jamialahmadi Oveis; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-alcoholic fatty liver disease; Polygenic risk score; Genomewide association studies; Mendelian Randomization;

   Sammanfattning : Non-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease, ranging from simple steatosis to more severe conditions, namely non-alcoholic steatohepatitis (NASH), liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). NAFLD has a strong genetic component, and its heritability depends on environmental factors and ethnicity. LÄS MER

7. 15. Interplay between genetics and environment in obesity

   Författare :Dmitry Shungin; Paul W Franks; Eivind Hovig; Umeå universitet; []
   Nyckelord :obesity; GWAS; gene-environment interactions; waist-hip ratio; body mass index; periodontitis; Mendelian randomization; heterogeneity of variance;

   Sammanfattning : Background. Being one of the largest current global health problems, obesity is a result of interplay between genetic and environmental factors. LÄS MER