Sökning: "randomised controlled trials"

Visar resultat 11 - 15 av 80 avhandlingar innehållade orden randomised controlled trials.

1. 11. Upper airway surgery in obstructive sleep apnoea : descriptive, observational and randomised controlled studies

   Författare :Nanna Browaldh; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Obstructive sleep apnoea syndrome (OSAS) is a general health problem which causes daytime sleepiness, impaired quality of life and increased morbidity and mortality. A narrow upper airway anatomy is a common cause of OSAS, and tracheostomy was the initial surgical treatment for OSAS. LÄS MER

3. 12. Philosophical controversies in the evaluation of medical treatments : With a focus on the evidential roles of randomization and mechanisms in Evidence-Based Medicine

   Författare :Alexander Mebius; John Cantwell; Jeremy Howick; Sven Ove Hansson; Julian Reiss; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HUMANIORA; HUMANITIES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Evidence; randomized controlled trials; observational studies; systematic reviews; meta-analysis; methodology; process assessment; outcome assessment; medical care; randomization; evidence-based medicine; selection bias; philosophy of medicine; philosophy of science; mechanisms; quality of evidence; animal studies; treatment effect; causation by absence; medical technology; Filosofi; Philosophy;

   Sammanfattning : This thesis examines philosophical controversies surrounding the evaluation of medical treatments, with a focus on the evidential roles of randomised trials and mechanisms in Evidence-Based Medicine. Current 'best practice' usually involves excluding non-randomised trial evidence from systematic reviews in cases where randomised trials are available for inclusion in the reviews. LÄS MER

4. 13. Self-Management of Urinary Incontinence Using eHealth : clinically relevant improvement, treatment effect and factors associated with success

   Författare :Emma Nyström; Eva Samuelsson; Malin Sjöström; Guri Rørtveit; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urinary incontinence; pelvic floor muscle training; eHealth; self-management; quality of life; randomised controlled trial; Family Medicine; allmänmedicin;

   Sammanfattning : Background: Urinary incontinence is common among women, with prevalence most often reported to be between 25% and 45%. The most common type is stress urinary incontinence (SUI), defined as leakage upon exertion. First-line treatment includes pelvic floor muscle training (PFMT) and lifestyle advice. LÄS MER

5. 14. Medication reviews by clinical pharmacists in older hospitalised patients : Implementation, performance and effects

   Författare :Thomas G. H. Kempen; Ulrika Gillespie; Håkan Melhus; Elisabet I. Nielsen; Derek Stewart; Stephen Byrne; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medication review; medication reconciliation; multi-professional collaboration; hospital medicine; polypharmacy; inappropriate prescribing; drug-related problems; medication-related hospital admissions; pragmatic clinical trial; cluster analysis; randomised controlled trial; qualitative analysis; process evaluation; implementation science; Geriatrics; Geriatrik; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy; Internal Medicine; Internmedicin; Hälso- och sjukvårdsforskning; Health Care Research;

   Sammanfattning : Background Inappropriate use of medications is a leading cause of avoidable harm in health care. Medication reviews by clinical pharmacists improve medication use, but evidence on hard clinical outcomes in older hospitalised patients is scarce and implementation in practice is challenging. LÄS MER

7. 15. Tamoxifen response in primary breast cancer with special reference to tumour-specific VEGF-A and VEGFR2

   Författare :Lisa Rydén; Lund Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; oncology; cancerology; Cytologi; onkologi; cancer; prognosis; randomised controlled trial; adjuvant tamoxifen treatment; vascular endothelial growth factor receptor 2; breast cancer; vascular endothelial growth factor A;

   Sammanfattning : Background: Treatment of primary breast cancer is individualised and adjuvant systemic treatment is delivered to most patients after surgery. Oestrogen receptor (ER) status and progesterone receptor status (PR) can define patients who would benefit from adjuvant endocrine therapy with tamoxifen (TAM) alone or as chemo-endocrine therapy. LÄS MER