Sökning: "radionuclide technique"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden radionuclide technique.

  1. 1. On Weapons Plutonium in the Arctic Environment (Thule, Greenland)

    Författare :Mats Eriksson; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nuclear physics; Kärnfysik; Nuclear medicine; radiobiology; Nukleärmedicin; radiobiologi; Nuclear engineering and technology; Kärnteknik; realtime digital image systems; SEM; ICP-MS; alpha spectrometry; gamma spectrometry; heterogeneous activity concentration; hot particle; separation technique; isotopic ratio; inventory; source term; fallout; americium; uranium; plutonium; radionuclide; Bylot Sound; Greenland; Thule; environmental radioactivity; nuclear accident;

    Sammanfattning : This thesis concerns a nuclear accident that occurred in the Thule (Pituffik) area, NW Greenland in 1968, called the Thule accident. Results are based on different analytical techniques, i.e. gamma spectrometry, alpha spectrometry, ICP-MS, SEM with EDX and different sediment models, i. LÄS MER

  3. 2. Inhibition of Calcium and Zinc Absorption by Phytate in Man Methodological Studies and Hydrothermal Processing of Cereals to Improve Absorption

    Författare :Kerstin Fredlund; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; barley; wheat; rye; 65Zn; oats; zinc absorption; whole grains; InsP6; hydrothermal processing; calcium absorption; rice; radionuclide technique; 47Ca; extrinsic labelling; phytate; hydrothermal treatment; myo-inositol; calcium retention; whole-body counting;

    Sammanfattning : A mathematical model based on measurements in a whole-body counter described the retention of calcium in the human body. It was shown that the relative retention of intravenous and orally administered 47Ca in all subjects (n = 10 - 11) were well described by fitting a simple function of time with two free parameters to a few whole-body measurements after day 6, when the unabsorbed calcium had been excreted. LÄS MER

  4. 3. Methods for image-based dosimetry and radiobiological modelling in radionuclide therapy

    Författare :Johan Gustafsson; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radionuclide therapy; dosimetry; biologically effective dose; 177Lu-DOTATATE;

    Sammanfattning : In radionuclide therapy (RNT), radioactive pharmaceuticals are administered for therapeutic purposes. Dosimetry, i.e. the estimation of the absorbed dose to various targets, can potentially lead to a better understanding of the therapeutic effects in RNT and allow for individualization of the therapy. LÄS MER

  5. 4. Effect of Uncertainty of Rock Properties on Radionuclide Transport by Groundwater : Implications for Performance Assessments of the Repository of Spent Nuclear Fuel in Heterogeneous Bedrock

    Författare :Shulan Xu; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Earth sciences; Radionuclide migration; heterogeneous rock property; stochastic process spectral analysis; temporal moments; auto-covariance functions; sorption kinetics; performance assessment; Geovetenskap; Earth sciences; Geovetenskap; Sedimentology; sedimentologi;

    Sammanfattning : The overall objective of the current study is to develop a quantitative understanding of the effects of spatial variability in physical and geochemical properties of crystalline rock on the migration of radionuclides along a single fracture in bedrock. A stochastic model was developed to describe the transport of solutes in fractured rock. LÄS MER

  7. 5. Molecular Radionuclide Imaging Using Site-specifically Labelled Recombinant Affibody Molecules : Preparation and Preclinical Evaluation

    Författare :Sara Ahlgren; Vladimir Tolmachev; Anna Orlova; Göran Hedenstierna; Joachim Feldwisch; Raymond Reilly; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molecular radionuclide imaging; Affibody molecules; HER2; cancer detection; radiolabelling; technetium; indium; cobalt; SPECT; PET; Oncology; Onkologi; Diagnostic radiology; Diagnostisk radiologi; Radiation biology; Strålningsbiologi; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Radionuclide molecular imaging is an emerging multidisciplinary technique that is used in modern medicine to visualise diseases at cellular and molecular levels. This thesis is based on five papers (I-V) and focuses on the development of site-specific radiolabelled recombinant anti-HER2 Affibody molecules and preclinical evaluations in vitro and in vivo of the labelled conjugates. LÄS MER