Sökning: "radiofysik"

Visar resultat 16 - 20 av 69 avhandlingar innehållade ordet radiofysik.

  1. 16. Alpha-radioimmunotherapy with At-211: Evaluations and imaging on normal tissues and tumors

    Författare :Tom Bäck; Göteborgs universitet.; Gothenburg University.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radioimmunotherapy; astatine; RBE; renal function; GFR; imaging; targeted radiotherapy; alpha-RIT;

    Sammanfattning : Alpha-radioimmunotherapy (alpha-RIT) is an internal conformal radiotherapy at the cellular level using alpha-particle emitting radionuclides. Alpha-particles have a very short range in tissues (... LÄS MER

  2. 17. Pharmacokinetics and dosimetry in intraperitoneal radioimmunotherapy with 211At

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Elin Cederkrantz; Göteborgs universitet.; Gothenburg University.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; astatine-211; radioimmunotherapy; alpha-emitter; ovarian cancer; MX35; pharmacokinetics; dosimetry; effective dose;

    Sammanfattning : The prognosis for patients diagnosed with disseminated cancer is often poor. Radioimmunotherapy (RIT) is a new approach to treat disseminated disease. The aim is to target tumor cells with monoclonal antibodies (mAbs) labeled with radionuclides which release cytotoxic particle radiation upon decay. The radionuclide 211At, with half-life 7. LÄS MER

  3. 18. Therapy of neuroendocrine tumors with 177Lu-octreotate - Human tumor cell types and models and optimization of treatment Terapi av neuroendokrina tumörer med 177Lu-octreotate

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Johanna Dalmo; Göteborgs universitet.; Gothenburg University.; Göteborgs universitet.; Gothenburg University.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; somatostatin; radionuclide therapy; receptor up-regulation; RBP; nephrotoxicity;

    Sammanfattning : Neuroendocrine (NE) tumors (NET) have often metastasized at the time of diagnose, which makes it hard to cure patients with NET. Radiolabeled hormone analogues (especially somatostatin analogues, SS) can be used for diagnostics (e.g. 111In-octreotide) and therapy (e. LÄS MER

  4. 19. Pretargeting agents and At-211-labeled effector molecules: Synthesis and preclinical evaluation for pretargeted alpha-radioimmunotherapy

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Sofia Frost; Göteborgs universitet.; Gothenburg University.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha particles; astatine-211; avidin; biotin; ovarian cancer; polylysine; pretargeted radioimmunotherapy;

    Sammanfattning : .... LÄS MER

  5. 20. Development of targeted alpha therapy with Bi-213 and At-211 for the treatment of disseminated cancer

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Anna Gustafsson; Göteborgs universitet.; Gothenburg University.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha particles; astatine; bismuth; MX35; ovarian cancer; polylysine; pretargeted radioimmunotherapy; radioimmunotherapy;

    Sammanfattning : Radioimmunotherapy (RIT) is a type of targeted cancer therapy. The concept behind RIT is to deliver cytotoxic ionizing radiation to tumor cells by attaching radionuclides to tumor-specific antibodies. LÄS MER