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Visar resultat 1 - 5 av 11 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Biomaterials for Promoting Self-Healing of Bone Tissue

    Författare :Sonya Piskounova; Jöns Hilborn; Tim Bowden; Simon Cool; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Osseointegration; implant coating; hyaluronan hydrogel; bone morphogenetic protein-2; hydroxyapatite; bone; delivery system; injectable; mixing; radioactive labeling; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

    Sammanfattning : The present work addresses poor bone/implant integration and severe bone defects. In both conditions external stimuli is required for new bone to form. LÄS MER

  3. 2. Accelerator Mass Spectrometry of 36Cl and 129I : Analytical Aspects and Applications

    Författare :Vasily Alfimov; Göran Possnert; Ala Aldahan; Hans-Arno Synal; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Environmental technology; Accelerator Mass Spectrometry; iodine-129; chlorine-36; gas-filled magnet; radioactive tracer; Arctic Ocean; Nordic Seas; North Atlantic; thermohaline circulation; Sellafield; La Hague; Miljöteknik; Environmental engineering; Miljöteknik;

    Sammanfattning : Two long-lived halogen radionuclides (36Cl, T1/2 = 301 kyr, and 129I, T1/2 = 15.7 Myr) have been studied by means of Accelerator Mass Spectrometry (AMS) at the Uppsala Tandem Laboratory. The 36Cl measurements in natural samples using a medium-sized tandem accelerator (~1 MeV/amu) have been considered. LÄS MER

  4. 3. Methodological advancements in microfluidic and carbonylation PET radiochemistry

    Författare :Kenneth Dahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Along with the progress of PET as a powerful imaging tool in medicine, there has been increasing demand for new labeling methods. The main aim of this PhD dissertation was to develop novel labeling methodologies using the positron emitter carbon-11. LÄS MER

  5. 4. Potential mechanisms for acute health effects and lung retention of inhaled particles of different origin

    Författare :Anna Klepczynska Nyström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Environmental particle exposure is known to have negative health effects. There is limited knowledge about how size and origin of particles influence these effects. There is also little known regarding the fate of ultrafine particles (particles in nanosize;< 100 nanometers in diameter) after being inhaled. LÄS MER

  7. 5. Protein modification with hydrophobic prenyl groups in malignant cells

    Författare :Magnus Hjertman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mevalonate (MVA) is the key intermediate in the isoprene synthetic pathway leading to the formation of a number of biologically important lipid molecules. It is well known that inhibition of MVA synthesis blocks the cell cycle progression of mammalian cells, a fact suggesting that some isoprenoids derived from MVA are required for cell proliferation. LÄS MER