Sökning: "radio-immunotherapy"

Hittade 2 avhandlingar innehållade ordet radio-immunotherapy.

  1. 1. Precision medicine and targeted therapy : Turning the tables on cancer

    Författare :Anja Mortensen; Marika Nestor; Gregory Adams; Uppsala universitet; []
    Nyckelord :p53 cancers; PM2; radiosensitization; radio-immunotherapy; MDM2 X inhibition; combination therapy; targeted radionuclide therapy; CD44v6; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap;

    Sammanfattning : An extended understanding of the molecular characteristics of cancer has led to a revolution within the field of precision medicine. This thesis explores the utilization of two targets for precision medicine, namely, CD44v6 and murine double-minute 2 and X (MDM2/X). LÄS MER

  3. 2. Towards Personalized Cancer Therapy : New Diagnostic Biomarkers and Radiosensitization Strategies

    Författare :Diana Spiegelberg; Marika Nestor; Bo Stenerlöw; Johan Lennartson; Theodosia Maina-Nock; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumor targeting; radionuclide targeting; HSP90 inhibition; AT13387; radiosensitization; molecular imaging; combination treatment; EGFR; CD44v6; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap;

    Sammanfattning : This thesis focuses on the evaluation of biomarkers for radio-immunodiagnostics and radio-immunotherapy and on radiosensitization strategies after HSP90 inhibition, as a step towards more personalized cancer medicine. There is a need to develop new tracers that target cancer-specific biomarkers to improve diagnostic imaging, as well as to combine treatment strategies to potentiate synergistic effects. LÄS MER