Sökning: "radical scavengers"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden radical scavengers.

  1. 1. Experimental cardiopulmonary cerebral resuscitation : with special reference to cerebral eicosanoid production and free radical scavengers

    Författare :Xiaoli Liu; Marianne Forsman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology and intensive care; cerebral resuscitation; reperfusion damage; oxidative injury; eicosanoid; free radical scavenger; neurological function; alkaline buffer; S-PBN; PBN; Anestesiologi och intensivvård; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anestesiologi; Anaesthesiology;

    Sammanfattning : Reperfusion injury after restoration of spontaneous circulation (ROSC) is often considered one of the predominant factors in determining neurological outcome in cardiac arrest. Therefore one of the main targets of experimental and clinical studies has been to mitigate this reperfusion injury. LÄS MER

  3. 2. Delayed Cell Death after Traumatic Brain Injury : Role of Reactive Oxygen Species

    Författare :Fredrik Clausen; Lars Hillered; Tiit Mathiesen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Traumatic Brain Injury; Reactive oxygen species; Fluid percussion injury; Controlled cortical impact; weight drop injury; Extracellular-signal regulated kinase; apoptosis; free radical scavenging; morphology; functional outcome; Neurovetenskap; Neurology; Neurologi;

    Sammanfattning : Traumatic brain injury (TBI) is a leading cause of death and disability TBI survivors often suffer from severe disturbances of cognition, memory and emotions. Improving the treatment is of great importance, but as of yet no specific neuroprotective treatment has been found. LÄS MER

  4. 3. Mechanisms of alloxan diabetogenicity

    Författare :Kjell Grankvist; Inge-Bert Täljedal; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alloxan; catalase; experimental diabetes; free radicals; islets of Langerhans; rubidium accumulation; superoxide dismutase; Trypan Blue;

    Sammanfattning : Suspensions of pancreatic islet cells from ob/ob-mice were incubated with Trypan Blue. Microscope photometry showed that apparently viable cells excluded the dye completely, whereas the nuclei of non-viable cells accumulated Trypan Blue by a saturable process. LÄS MER

  5. 4. Redox effects on neutrophils in wound healing conducted by wound dressings and hyperbaric oxygen

    Författare :Herman Sahlin; Göteborgs universitet; []
    Nyckelord :neutrophil granulocyte; wound healing; wound dressing; reactive oxygen species; NO; hyperbaric oxygen; bacterial killing;

    Sammanfattning : The increased influx of neutrophils into chronic wounds results in increased production of reactive oxygen species (ROS), nitric oxide (NO) and lipid peroxidation products (LPP), as well as a ROS-induced increase in protease levels. The NO and LPP impair the respiratory burst response of the neutrophils and reduce their capacity to kill bacteria and digest debris. LÄS MER

  7. 5. Developmental disturbances of the embryo in diabetic pregnancy

    Författare :Parri Wentzel; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; diabetes; pregnancy; embryo; malformation; glucose; ROS; SOD; NAC; prosta- glandin; COX; COX inhibitor; gene expression; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Maternal diabetes during pregnancy constitutes an increased risk for congenital malformation in the offspring. Previous studies have suggested that diabetic embryopathy is associated with an excess of reactive oxygen species (ROS) as well as with a disturbance of prostaglandin (PG) metabolism. LÄS MER