Sökning: "radiation quality"

Visar resultat 16 - 20 av 303 avhandlingar innehållade orden radiation quality.

1. 16. Optical Studies For Synchrotron Radiation Beamlines

   Författare :Walan Grizolli; Lunds universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Synchrotron Radiation; Optics; X-ray Optics; Beamline; Polarimetry; Coherence; Storage Rings; Diffraction Limited Storage Rings;

   Sammanfattning : Synchrotron radiation sources have greatly contributed to the progress in many fields of science. The development of the storage ring technologies has made possible to obtain very low emittance electron beams, which together with the use of undulators allow guiding a very high photon flux into a very small spot required by the experiments. LÄS MER

3. 17. Toward Robust Optimization of Adaptive Radiation Therapy

   Författare :Michelle Böck; Anders Forsgren; Minsun Kim; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; optimization; adaptive radiation therapy; radiation therapy treatment planning; uncertainty; robust optimization; stochastic programming; Tillämpad matematik och beräkningsmatematik; Applied and Computational Mathematics;

   Sammanfattning : Adaptive radiation therapy is an evolving cancer treatment approach which relies on adapting the treatment plan in response to patient-specific interfractional geometric variations occurring during the fractionated treatment. If those variations are not addressed through adaptive replanning, the resulting treatment quality may be compromised. LÄS MER

4. 18. Biomarkers of ionising radiation relevant to carcinogenesis : Dose, dose rate and LET dependency of the responses

   Författare :Milagrosa López Riego; Andrzej Wojcik; Lovisa Lundholm; Alexandros G. Georgakilas; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ionising radiation; low dose; low dose rate; linear energy transfer LET ; mixed beams; dose and dose rate effectiveness factor DDREF ; cancer; DNA damage response; biomarkers; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : A better understanding of the relationship between ionising radiation (IR) dose, dose rate and radiation quality, and the risk of stochastic effects would improve risk extrapolation from atomic bomb survivors’ data. Owing to insufficient statistical power of epidemiological studies to detect excess incidence of cancer following low doses of IR delivered at low dose rates (LDLDR), as typically encountered in most common human exposure scenarios, radiobiological experiments are fundamental to describe the biological effectiveness of LDLDR and to define the underlying molecular mechanisms. LÄS MER

5. 19. Radiation-induced dysphagia in head and neck cancer - risk structures and methodological aspects

   Författare :Johanna Hedström; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; head and neck cancer; radiation therapy; dysphagia; patient-reported outcomes; quality of care;

   Sammanfattning : Background/Aims: Swallowing difficulties are common after radiation therapy (RT) in head and neck cancer (HNC). The overall aim of this thesis was to address radiation-induced late dysphagia with regard to investigating anatomical risk structures related to the development of radiation-induced dysphagia, as well as methodological aspects in the evaluation of swallowing. LÄS MER

7. 20. Factors modifying cellular response to ionizing radiation

   Författare :Lei Cheng; Andrzej Wojcik; Siamak Haghdoost; Lovisa Lundholm; Penelope A. Jeggo; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Radiation biology; DNA damage; gene expression; alpha particles; X-rays; mixed beams; gamma rays; hypothermia; dose rate.; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : Many physical factors influence the biological effect of exposure to ionizing radiation, including radiation quality, dose rate and temperature. This thesis focuses on how these factors influence the outcome of exposure and the mechanisms behind the cellular response. LÄS MER