Sökning: "radiation damage"

Visar resultat 16 - 20 av 236 avhandlingar innehållade orden radiation damage.

  1. 16. On Microvascular Inflammation and Intestinal Leakage in Radiation Enteropathy

    Författare :Andrada Röme; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiation; colon; intestinal leakage; Leukocyte and platelet recruitment;

    Sammanfattning : Gastrointestinal tract damage is an insidious feature in patients undergoing radiotherapy. Microvascular inflammation, including leukocyte and platelet recruitment as well as epithelial barrier dysfunction, are considered to constitute key components in the pathophysiology of radiation-induced enteropathy. LÄS MER

  2. 17. Biomarkers of ionising radiation relevant to carcinogenesis : Dose, dose rate and LET dependency of the responses

    Författare :Milagrosa López Riego; Andrzej Wojcik; Lovisa Lundholm; Alexandros G. Georgakilas; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ionising radiation; low dose; low dose rate; linear energy transfer LET ; mixed beams; dose and dose rate effectiveness factor DDREF ; cancer; DNA damage response; biomarkers; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : A better understanding of the relationship between ionising radiation (IR) dose, dose rate and radiation quality, and the risk of stochastic effects would improve risk extrapolation from atomic bomb survivors’ data. Owing to insufficient statistical power of epidemiological studies to detect excess incidence of cancer following low doses of IR delivered at low dose rates (LDLDR), as typically encountered in most common human exposure scenarios, radiobiological experiments are fundamental to describe the biological effectiveness of LDLDR and to define the underlying molecular mechanisms. LÄS MER

  3. 18. Ultraviolet Radiation and Squamous Cell Carcinoma in Human Skin

    Författare :Cecilia Wassberg; Olle Larkö; Uppsala universitet; []
    Nyckelord :Medical sciences; Ultraviolet radiation; squamos cell carcinoma; incidence; sunscreens; p53; DNA damage; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Dermatology and Venerology; dermatologi och venereologi;

    Sammanfattning : Ultraviolet radiation (UVR) is a major risk factor for development of skin cancer. UVR-induced DNA damage and a dysfunctional p53 protein are important steps in the development of squamous cell carcinoman in human skin (SCC). LÄS MER

  4. 19. Cellular responses to combined irradiation with alpha particles and X-rays

    Författare :Alice Sollazzo; Andrzej Wojcik; Alexandros Georgakilas; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Radiation; DNA damage; mutations; alpha particles; X-rays; mixed beam; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Mixed radiation fields, where different ionizing particles act together, are very important in radiobiology and in radiation protection. Mixed beams are not only the most common form of radiation exposure, but the prediction of their biological effect is also full of uncertainties. LÄS MER

  5. 20. Radiation tests of semiconductor detectors

    Författare :Valery Chmill; Bengt Lund-Jensen; Richar Brenner; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; radiation physics; materials science; Nuclear physics; Kärnfysik;

    Sammanfattning : This thesis investigates the response of Gallium Arsenide (GaAs) detectors to ionizing irradiation. Detectors based on π-υ junction formed by deep level centers doping. LÄS MER