Sökning: "quinoline-3-carboxamide"

Visar resultat 6 - 7 av 7 avhandlingar innehållade ordet quinoline-3-carboxamide.

  1. 6. Modulation of experimental T cell autoimmunity in the nervous system with emphasis on nasal tolerance

    Författare :Xue-Feng Bai; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Experimental autoimmune neuritis (EAN) and encephalomyelitis (EAE) are animal models of Guillian-Barre syndrome (GBS) and multiple sclerosis (MS), representing human demyelinating diseases of the peripheral nervous system (PNS) and central nervous system (CNS), respectively. CD4+ T cells recognizing myelin antigens and producing cytokines play central roles in the pathogenesis of both EAN and EAE and perhaps of GBS and MS. LÄS MER

  3. 7. Modulation of Autoimmunity by Linomide treatment or interference with costimulation

    Författare :Annamaria C Tellander; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; collagen-induced arthritis; CD28; CD40; antigen presenting cells; Linomide; thymocytes; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : Linomide is a potent immunomodulator that has been shown to inhibit autoimmunity in several animal models of autoimmune disease. We have approached the cellular and molecular mechanism of Linomide by investigating its effect on thymocyte development and its capacity to modulate the expression of activation markers on antigen presenting cells (APCs). LÄS MER