Sökning: "quantitative models"

Visar resultat 6 - 10 av 700 avhandlingar innehållade orden quantitative models.

  1. 6. Quantitative Laser Doppler Flowmetry

    Författare :Ingemar Fredriksson; Tomas Strömberg; Marcus Larsson; Weindelt Stenbergen; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Medical engineering; Medicinsk teknik;

    Sammanfattning : Laser Doppler flowmetry (LDF) is virtually the only non-invasive technique, except for other laser speckle based techniques, that enables estimation of the microcirculatory blood flow. The technique was introduced into the field of biomedical engineering in the 1970s, and a rapid evolvement followed during the 1980s with fiber based systems and improved signal analysis. LÄS MER

  2. 7. Quantitative diffuse reflectance spectroscopy : myocardial oxygen transport from vessel to mitochondria

    Författare :Tobias Lindbergh; Tomas Strömberg; Henrik Ahn; Marcus Larsson; Lise Lyngsnes Randeberg; Linköpings universitet; []
    Nyckelord :TECHNOLOGY; TEKNIKVETENSKAP;

    Sammanfattning : In the field of biomedical optics, diffuse reflectance spectroscopy (DRS) is a frequently used technique for obtaining information about the optical properties of the medium under investigation. The method utilizes spectral difference between incident and backscattered light intensity for quantifying the underlying absorption and scattering processes that affects the light-medium interaction. LÄS MER

  3. 8. Affinity-, Partition- and Permeability Properties of the Human Red Blood Cell Membrane and Biomembrane Models, with Emphasis on the GLUT1 Glucose Transporter

    Författare :Christine Lagerquist Hägglund; Per Lundahl; Jørgen Vinten; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Affinity; Aromatic amino acids; Binding; Biomembrane; Biotin; Chromatography; Cytochalasin B; Dihydrocytochalasin B; Dissociation constant; Drug absorption; Ethanol; Equilibrium; Glucose; GLUT1; Immobilization; Immobilized biomembrane affinity chromatography; Immobilized liposome chromatography; Interaction; Liposome; Membrane protein; Membrane vesicle; Partitioning; Phospholipid bilayer; Proteoliposome; Quantitative; Red blood cell; Specific; Streptavidin; Tyrosine; Tryptophan; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : The human glucose transporter GLUT1 is abundant in red blood cells, the blood-brain barrier and epithelial cells, where it mediates the transport of the energy metabolite, glucose. In the present work some properties of GLUT1, including affinity binding of both substrates and inhibitors, transport rates as well as permeabilities of aromatic amino acids and drug-membrane interactions were analyzed by chromatographic methods. LÄS MER

  4. 9. Contributions to quantitative dynamic contrast-enhanced MRI

    Författare :Anders Garpebring; Mikael Karlsson; Ronnie Wirestam; Nils Östlund; Jón Hauksson; Steven Sourbron; Umeå universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Dynamic contrast-enhanced MRI; quantitative imaging; parameter estimation; uncertainty estimation; arterial input function; radiofysik; radiation physics;

    Sammanfattning : Background: Dynamic contrast-enhanced MRI (DCE-MRI) has the potential to produce images of physiological quantities such as blood flow, blood vessel volume fraction, and blood vessel permeability. Such information is highly valuable, e.g., in oncology. LÄS MER

  5. 10. Quantitative methods for diffusion measurements in fluorescence microscopy

    Författare :Marco Longfils; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cross-validation.; single particle tracking; Confocal laser scanning microscopy; raster scan; correlation spectroscopy; mixture models; diffusion;

    Sammanfattning : In this work, statistical methods are developed for mapping mass transport locally based on images collected using a confocal laser scanning microscope. Besides presenting raster image correlation spectroscopy as an established method in fluorescence microscopy, we introduce a single particle tracking method which takes advantage of the raster scanning of the image in a confocal microscope. LÄS MER