Sökning: "quantitative methods"
Visar resultat 1 - 5 av 1997 avhandlingar innehållade orden quantitative methods.
1. Quantitative Bioanalysis : Liquid separations coupled to targeted mass spectrometric measurements of bioactive compounds
Sammanfattning : Performing quantitative analysis of targeted bioactive compounds in biological samples, such as blood plasma, cerebrospinal fluid or extracts from pig liver, put high demands on the ruggedness of the method acquiring the results. In addition to the complexity of the sample matrix, the bioactive compounds targeted for analysis usually have low levels of natural abundance, further increasing the demand on the analytical method sensitivity. LÄS MER
2. Novel Statistical Methods in Quantitative Genetics : Modeling Genetic Variance for Quantitative Trait Loci Mapping and Genomic Evaluation
Sammanfattning : This thesis develops and evaluates statistical methods for different types of genetic analyses, including quantitative trait loci (QTL) analysis, genome-wide association study (GWAS), and genomic evaluation. The main contribution of the thesis is to provide novel insights in modeling genetic variance, especially via random effects models. LÄS MER
3. Pharmacometric Models to Improve Treatment of Tuberculosis
Sammanfattning : Tuberculosis (TB) is the world’s most deadly infectious disease and causes enormous public health problems. The comorbidity with HIV and the rise of multidrug-resistant TB strains impede successful therapy through drug-drug interactions and the lack of efficient second-line treatments. LÄS MER
4. Quantitative imaging with PET : performance and applications of 76Br, 52Fe, 110mIn and 134La
Sammanfattning : The use of positron emission tomography (PET) has so far mainly been limited to a few nuclides with short half-lives such as 11C and 18F. Certain applications require nuclides with longer half-lives, such as 76Br and 52Fe. LÄS MER
5. Laboratory X-Ray Phase-Contrast Imaging : Methods and Comparisons
Sammanfattning : X-ray phase-contrast imaging has seen rapid development in recent decades due to its superior performance in imaging low-absorption objects, compared to traditional attenuation x-ray imaging. Having higher demand on coherence, x-ray phase-contrast imaging is performed mostly at synchrotrons. LÄS MER