Sökning: "pulmonary leukocyte recruitment"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden pulmonary leukocyte recruitment.

  1. 1. Platelet-dependent pulmonary recruitment of neutrophils in abdominal sepsis

    Författare :Milladur Rahman; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; abdominal sepsis; neutrophil recruitment; platelet; lung injury;

    Sammanfattning : Sepsis and subsequent multiple organ failure remain the major cause of mortality in intensive care units. Leukocyte-mediated tissue damage is a key feature in septic lung injury. Accumulating data suggest that platelets play a role in inflammation and tissue injury. LÄS MER

  3. 2. Pancreatitis-Associated Pulmonary Injury

    Författare :Xia Zhao; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; orthopaedics; Surgery; inflammatory mediators; protein kinase C; leukocytes; acute lung injury; abdominal sepsis; acute pancreatitis; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : In acute pancreatitis (AP), lung injury is an early occuring and important part of the multiple organ dysfunction syndrome. The mechanisms underlying the development of lung injury though still largely remains unclear. LÄS MER

  4. 3. In vivo imaging of leukocyte-endothelium interactions in septic lung injury

    Författare :Jonas Roller; Kirurgi; []
    Nyckelord :Sepsis; Acute lung injury; Leukocyte recruitment; Intravital fluorescence microscopy;

    Sammanfattning : Excessive accumulation of leukocytes in the lung represents a key feature in the development of an acute lung injury (ALI). Numerous studies demonstrated that leukocyte rolling is a compulsory precondition for the firm adhesion in organs. However, it seems that the recruitment process of leukocytes in the lung is more complex. LÄS MER

  5. 4. Effects of Inflammatory Mediators on Pulmonary Airways

    Författare :Ofir Bachar; Klinisk och experimentell allergiforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electric ?eld stimulation; bradykinin; airway; tumor necrosis factor a; Respiratory system; nitric oxide; Andningsorganen; Toll-like receptor; prostaglandin E2; neurotrophin; allergy;

    Sammanfattning : Chronic inflammation is together with excessive contraction of the airways key features of asthma. The aims of the thesis were to analyze the effect of inflammatory mediators on airway smooth muscle, using an in vitro model of cultured murine airways. LÄS MER

  7. 5. Isoprenylation and NET formation in acute pancreatitis

    Författare :Mohammed Merza; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute pancreatitis; neutrophil recruitment; trypsinogen activation; NET;

    Sammanfattning : Acute Pancreatitis (AP) is an inflammation disease that characterized by activation of protease and the innate immune system, leading to infiltration of neutrophils and tissue damage in the pancreas. The aim of this thesis was to determine the role of isoprenylation (farnesyltransferase and geranylgeranyltransferase) as well as NET formation in regulating recruitment of neutrophils and tissue damage in severe AP. LÄS MER