Sökning: "pulchral"

Hittade 2 avhandlingar innehållade ordet pulchral.

1. 1. SARs for the Antiparasitic Plant metabolite Pulchrol

   Författare :Paola Terrazas Villarroel; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; pulchrol; pulchral; SARs; antiparasitic; Leishmania braziliensis; Leishmania amazonensis; Trypanozoma cruzi; Bourreria pulchra; Leishmaniasis; Chagas disease; Synthesis; Pharmacophore; ADMET;

   Sammanfattning : Pulchrol, a natural compound isolated from the roots of the vegetal specie Bourreria pulchra has been shown to possess potential antiparasitic activity toward Trypanosomatids, particularly against Trypanosoma cruzi, which causes the Chagas disease; and moderately against Leishmania species, responsible for Leishmaniasis. In this investigation, several pulchrol analogues were prepared and assayed toward T. LÄS MER

3. 2. Synthesis of bioactive natural products and analogues

   Författare :Dan Killander; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SAR; natural product; total synthesis; benzochromene; fluorene; cannabinoid; statin; TRPA1; TSLP; antiprotozoal; nociception; asthma; inflammation;

   Sammanfattning : Natural products have until recently provided the only remedy for treatment of diseases. The development of modern chemistry in the last centuries has opened the door for tapping into the chemical diversity found in nature. Synthetic natural products, together with analogues, are an important piece in the puzzle towards curing many ailments. LÄS MER