Sökning: "protoporphyrin IX"
Visar resultat 1 - 5 av 26 avhandlingar innehållade orden protoporphyrin IX.
1. On the use of light for the characterization and treatment of malignant tumours
Sammanfattning : Some aspects on the use of light for tissue characterization and treatment of malignant tumours are discussed within this thesis. The work presented aims at improving optical techniques for tissue characterization, especially to detect malignant and pre-malignant lesions. LÄS MER
2. Photodynamic therapy and diagnosis of skin cancer : an investigation of photobleaching and technique optimisation
Sammanfattning : .... LÄS MER
3. Fluorescence imaging and non-linear spectroscopy for high-pressure catalysis studies and skin cancer demarcation
Sammanfattning : .... LÄS MER
4. An Investigation of Peroxidase Activity in Biomimetic and Biological Systems
Sammanfattning : In order to create a heme environment which permits biomimicry of heme-containing plant peroxidases and investigate the role played by the vinyl side chains of the porphyrin ring on the stability and, possibly, catalytic activity of model compounds, a number of new synthetic microperoxidases -– hemin-6(7)-gly-his methyl ester (HGH) and hemin-6(7)-gly-gly-his methyl ester (HGGH) and hemin-6,7-bis(gly-gly-his methyl ester) (H2GGH) as well as mesohemin-6(7)-gly-gly-his methyl ester (MGGH) and deuterohemin-6(7)-gly-gly-his methyl ester (DGGH) have been prepared by condensation of a peptide residue with the propionic side chains of hemin, mesohemin and deuterohemin, respectively. Reactivity studies towards different organic and inorganic substrates showed that not only five- but also six-coordinate hemin peptide complexes catalyze the oxidation of substrates by H2O2. LÄS MER
5. Photodynamic therapy and laser-based diagnostic studies of malignant tumours
Sammanfattning : Two non-thermal regimens of light interaction with biological tissue, that are in a natural way connected, are discussed in the present thesis. These are photodynamic therapy (PDT) for the treatment of malignant tumours and laser-induced fluorescence (LIF) for tissue characterization. LÄS MER