Sökning: "protooncogenes"

Hittade 2 avhandlingar innehållade ordet protooncogenes.

1. 1. Hormonal regulation of sex steroid receptors and growth related genes in human myometrium and leiomyomas

   Författare :Katarina Englund; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Uterus; leiomyoma; steroid receptor; protooncogenes; IGF-I; EGF.;

   Sammanfattning : Uterine fibroids, or leiomyomas, are the most common benign tumors in the female genital tract.They represent a major cause of gynaecologic morbidity. The etiology of these tumors is largely unknown but the levels of estrogen (E) and progesterone (P) are considered to be the major determinants for fibroid growth. LÄS MER

3. 2. Environmental Contaminants, Recombination and Cancer : Investigations on the molecular mechanisms of spontaneous and induced recombination in the hprt gene of Chinese hamster cells

   Författare :Thomas Helleday; Mark Meuth; Stockholms universitet; []
   Nyckelord :toxikologisk genetik; Genetic Toxicology;

   Sammanfattning : Recombination results in rearrangement of the genetic material contained in the chromosomes inherited from the mother and father and this process is also involved in repairing damage to the genome. Occasionally, the machinery that performs recombination malfunctions and this may lead to illegitimate recombination events which inactivate tumor suppressor genes or activate protooncogenes. LÄS MER