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Visar resultat 1 - 5 av 27 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Choreography of a proton pump : Studies of charge-transfer reactions in cytochrome c oxidase

    Författare :Jóhanna Vilhjálmsdóttir; Peter Brzezinski; Joachim Heberle; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; heme-copper oxidase; cytochrome c oxidase; respiration; proton pump; electron transfer; proton transfer; proton-transfer pathway; midpoint potential; proton-pumping mechanism; Biochemistry; biokemi;

    Sammanfattning : In the last step of cellular respiration, electrons from metabolites are transferred to molecular oxygen, mediated by the enzyme complexes of the respiratory chain. Some of these enzyme complexes couple these redox reactions to formation of an electrochemical proton gradient across the cell membrane. The proton gradient is used e.g. LÄS MER

  2. 2. Nitric Oxide Reductase from Paracoccus denitrificans : A Proton Transfer Pathway from the “Wrong” Side

    Författare :Ulrika Flock; Pia Ädelroth; Simon de Vries; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; denitrification; nitric oxide reductase; heme copper oxidase superfamily; divergent member; proton transfer; electron transfer; single turnover; spectroscopy; periplasm; glutamate; proton pathway; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Denitrification is an anaerobic process performed by several soil bacteria as an alternative to aerobic respiration. A key-step in denitrification (the N-N-bond is made) is catalyzed by nitric oxide reductase (NOR); 2NO + 2e- + 2H+ → N2O + H2O. LÄS MER

  3. 3. Electron and proton transfer in cytochrome c oxidase

    Författare :Magnus Brändén; Peter Rich; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytochrome c oxidase; electron transfer; proton transfer; proton; Biochemistry; Biokemi; biokemi; Biochemistry; Biophysics; biofysik;

    Sammanfattning : This doctoral thesis describes results from studies on the mechanisms by which the enzyme cytochrome c oxidase catalyses the reduction of oxygen to water. Cytochrome c oxidase is the last integral enzyme complex of the socalled respiratory chain in the mitochondrial inner membrane (plasma membrane of bacteria). LÄS MER

  4. 4. Proton transfer in nitric oxide reducing heme-copper oxidases

    Författare :Joachim Reimann; Pia Ädelroth; Peter Brzezinski; Michael Wilson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; heme-copper oxidases; nitric oxide; proton transfer; electron transfer; proton-transfer pathway; Biochemistry; biokemi;

    Sammanfattning : Heme-copper oxidases (HCuOs) are best known as terminal oxidases in the aerobic respiratory chain, in which they catalyze the reduction of oxygen to water. By receiving protons and electrons from opposite sides of the membrane as well as pumping protons, HCuOs contribute to the electrochemical proton gradient over the membrane that can be used for ATP synthesis. LÄS MER

  5. 5. Proton pathways in energy conversion : K-pathway analogs in O2- and NO-reductases

    Författare :Nathalie Gonska; Pia Ädelroth; Alessandro Giuffré; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; heme-copper oxidase; cytochrome c oxidase; membrane protein; respiration; electron transfer; proton transfer; redox reaction; metalloprotein; non-heme iron; cytochrome ba3; flow-flash; carbon monoxide; liposome; respiratory control ratio; Biochemistry; biokemi;

    Sammanfattning : Oxygen and nitric oxide reductases are enzymes found in aerobic and anaerobic respiration, respectively. Both enzyme groups belong to the superfamily of Heme-Copper Oxidases, which is further divided into several subgroups: oxygen-reducing enzymes into A-, B- and C-type and nitric oxide reductases into qNORs and cNORs. LÄS MER