Sökning: "proton pumping"

Visar resultat 1 - 5 av 42 avhandlingar innehållade orden proton pumping.

  1. 1. Choreography of a proton pump : Studies of charge-transfer reactions in cytochrome c oxidase

    Författare :Jóhanna Vilhjálmsdóttir; Peter Brzezinski; Joachim Heberle; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; heme-copper oxidase; cytochrome c oxidase; respiration; proton pump; electron transfer; proton transfer; proton-transfer pathway; midpoint potential; proton-pumping mechanism; Biochemistry; biokemi;

    Sammanfattning : In the last step of cellular respiration, electrons from metabolites are transferred to molecular oxygen, mediated by the enzyme complexes of the respiratory chain. Some of these enzyme complexes couple these redox reactions to formation of an electrochemical proton gradient across the cell membrane. The proton gradient is used e.g. LÄS MER

  3. 2. Electron and proton transfer in cytochrome c oxidase

    Författare :Magnus Brändén; Peter Rich; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytochrome c oxidase; electron transfer; proton transfer; proton; Biochemistry; Biokemi; biokemi; Biochemistry; Biophysics; biofysik;

    Sammanfattning : This doctoral thesis describes results from studies on the mechanisms by which the enzyme cytochrome c oxidase catalyses the reduction of oxygen to water. Cytochrome c oxidase is the last integral enzyme complex of the socalled respiratory chain in the mitochondrial inner membrane (plasma membrane of bacteria). LÄS MER

  4. 3. Proton, Electron, and O2 transfer in Cytochrome c Oxidase

    Författare :Lina Salomonsson; Peter Brzezinski; Marilyn Gunner; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytochrome c oxidase; electron transfer; proton transfer; proton pumping; kinetic isotope effect; Biochemistry; Biokemi;

    Sammanfattning : In mitochondria and aerobic bacteria energy conservation involves electron transfer through the membrane-bound protein of the respiratory chain to oxygen. Cytochrome c oxidase (CcO) catalyzes the reduction of oxygen to water. Part of the energy released in this reaction is used to pump protons across the membrane. LÄS MER

  5. 4. Active Transport of Ions across Biomembranes : A Kinetic Study of Cytochrome c Oxidase Reconstituted into Phospholipid Vesicles

    Författare :Kristina Faxén; Peter Brzezinski; Pia Ädelroth; Thomas E. DeCoursey; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytochrome c oxidase; electron transfer; proton transfer; proton pumping; kinetic isotop effect; ion pumping; flow flash; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Ion transport across membranes is of uttermost importance for us. It is the foundation for signaling of various kinds e.g. in the nerve-system. LÄS MER

  7. 5. Experimental studies of proton translocation reactions in biological systems : Electrogenic events in heme-copper oxidases

    Författare :Håkan Lepp; Peter Brzezinski; Thomas Nilsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; heme-copper oxidase; cytochrome c oxidase; nitric oxide reductase; cbb3-type oxidase; proton pumping; uncoupling; charge-transfer; electrogenic event; flow-flash; Biophysics; Biofysik; Biophysics; biofysik;

    Sammanfattning : Terminal heme-copper oxidases (HCuOs) are transmembrane proteins that catalyze the final step in the respiratory chain - the reduction of O2 to H2O, coupled to energy conservation by generation of an electrochemical proton gradient. The most extensively investigated of the HCuOs are the aa3-type oxidases, to which cytochrome c oxidase (CytcO) belongs, which uses energy released in the O2-reduction for proton pumping. LÄS MER