Sökning: "proton pump"

Visar resultat 11 - 15 av 74 avhandlingar innehållade orden proton pump.

  1. 11. Kinetics of proton and electron transfer in heme-copper oxidases

    Författare :Peter Lachmann; Pia Ädelroth; Örjan Hansson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Heme-copper oxidase; electron transfer; proton transfer; nitric oxide reductase; ba3 oxidase; flow-flash; laser-flash photolysis; Biochemistry; biokemi;

    Sammanfattning : Heme-copper oxidases are transmembrane proteins that are found in aerobic and anaerobic respiratory chains. During aerobic respiration, these enzymes reduce dioxygen to water. The energy released in the reaction is used to transport protons across a biological membrane. LÄS MER

  3. 12. Active Transport of Ions across Biomembranes : A Kinetic Study of Cytochrome c Oxidase Reconstituted into Phospholipid Vesicles

    Författare :Kristina Faxén; Peter Brzezinski; Pia Ädelroth; Thomas E. DeCoursey; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytochrome c oxidase; electron transfer; proton transfer; proton pumping; kinetic isotop effect; ion pumping; flow flash; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Ion transport across membranes is of uttermost importance for us. It is the foundation for signaling of various kinds e.g. in the nerve-system. LÄS MER

  4. 13. Structure and Function of Cytochrome c Oxidase

    Författare :Gisela Brändén; Peter Brzezinski; Mårten Wikström; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytochrome c oxidase; proton pumping; proton transfer; electron transfer; X-ray crystallography; flow flash; Biochemistry; Biokemi;

    Sammanfattning : Aerobic organisms, ranging from bacteria to humans, obtain their energy through the process of respiration. Electrons from the breakdown of food are transported through the membrane-bound enzyme complexes of the respiratory chain, to the terminal acceptor molecule, oxygen. LÄS MER

  5. 14. Pharmacodynamic Modelling of Irreversible and Reversible Gastric Proton Pump Inhibitors

    Författare :Angela Äbelö; Mats Karlsson; Michael Looby; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacokinetics Pharmacotherapy; Farmakokinetik Farmakoterapi; PHARMACY; FARMACI;

    Sammanfattning : Acid related diseases like GERD, duodenal-and gastric ulcers and H. Pylori-positive peptic ulcer disease are primarily managed by reducing gastric acidity. Irreversible proton pump inhibitors (PPIs) inhibit gastric acid secretion effectively throughout the day by irreversibly inhibiting the gastric proton pump, H+, K+-ATPase, in the parietal cells. LÄS MER

  7. 15. Degranulation in macrophages and other leukocytes: regulation by calcium, phosphoinositide 3-kinase, and protein kinase C

    Författare :Claes Nauclér; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lysosomal secretion; neutrophil; Clinical biology; proton pump; Klinisk biologi; exocytosis; lysosomal pH;

    Sammanfattning : Macrophages mediate innate immunity through release of cytokines, eicosanoids, reactive oxygen species as well as through phagocytosis and secretion of lysosomal enzymes. Regulation of lysosomal secretion in macrophages differs in several respects from release of specialized granules in other leukocytes. LÄS MER