Sökning: "prothrombin"

Visar resultat 11 - 15 av 40 avhandlingar innehållade ordet prothrombin.

  1. 11. The regulation of factor Va activity by activated protein C -Importance of the individual activated protein C cleavage sites in factor Va

    Författare :Eva Norström; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellulära vätskor; Hematologi; extracellular fluids; Haematology; activated protein C resistance; activated protein C; Blood coagulation; Factor V;

    Sammanfattning : The subject of this thesis is the activated protein C (APC)-mediated inactivation of factor Va. The activated form of factor V (FVa) is a procoagulant cofactor for Factor Xa (FXa) in the conversion of prothrombin to thrombin. LÄS MER

  3. 12. Synthesis, Function, and Inactivation of Blood Coagulation Factor V

    Författare :Kristoffer Sørensen; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; activated protein C; heparin; calcium binding; R2 haplotype; Blood Coagulation; Factor V; Clinical chemistry; Klinisk kemi;

    Sammanfattning : Blood coagulation factor V (FV) is a 330 kDa plasma glycoprotein. Activated FV (FVa) is a non-enzymatic cofactor to activated Factor X in the activation of prothrombin that occurs during coagulation. LÄS MER

  4. 13. Pro- and anticoagulant mechanisms in coronary artery disease. Clinical studies on factor VII and resistance to activated protein C

    Författare :Johan Holm; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein C; Factor VII; blood coagulation; myocardial infarction; APC resistance; Cardiovascular system; Kardiovaskulära systemet; warfarin;

    Sammanfattning : The triggering mechanism in myocardial infarction (MI) and unstable angina involves coronary thrombus formation following plaque rupture. Coagulation is initiated by tissue factor that activates factor VII (FVII), and is inhibited by protein C and its co-factor protein S. LÄS MER

  5. 14. Management of hemorrhagic complications associated with antithrombotic therapy

    Författare :Ammar Majeed; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Anticoagulants are used for the prevention and treatment of arterial and venous thromboembolism. Such therapy is always associated with an increased risk of bleeding. Intracranial hemorrhage is the most serious form of anticoagulantsrelated bleeding and caries a high mortality rate. LÄS MER

  7. 15. The regulation of blood coagulation by high-density lipoprotein particles

    Författare :Cecilia Oslakovic; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : High-density lipoprotein (HDL) has anti-atherogenic properties and the plasma level of HDL cholesterol correlates inversely with the risk of coronary artery disease. The atheroprotective functions of HDL can be explained by its function in the reverse cholesterol transport. LÄS MER