Sökning: "prothrombin fragment 1 2"

Visar resultat 6 - 10 av 14 avhandlingar innehållade orden prothrombin fragment 1 2.

  1. 6. The effect of thrombin inhibitors on coagulation activity and generation of activated protein C

    Författare :Rikard Linder; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The direct thrombin inhibitor inogatran was, in the TRIM trial (n=1209), compared with unfractionated heparin (UFH) concerning the effect on cardiovascular end-points in unstable coronary artery disease. The results in TRIM demonstrated a trend towards a benefit for UFH during the treatment phase, which was reduced after drug withdrawal. LÄS MER

  3. 7. Cellular markers indicating activation of the hemostatic system : studies on platelets and leukocytes in peripheral human blood

    Författare :Andreia Bunescu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Platelet activation is supposed to initiate thrombus formation in many clinical settings such as coronary artery occlusions, stroke, diabetes mellitus complications, and in surgical interventions. Coagulation and thrombosis are also associated with inflammation in septicemia. LÄS MER

  4. 8. Coagulation, fibrinolysis and inflammation in open surgery for infrarenal abdominal aortic aneurysm

    Författare :Anders Holmberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Abdominal aortic aneurysm; blood coagulation; fibrinolysis; cytokines; leucocytes; flow cytometry; chemotaxis; lactoferrin; myeloperoxidase; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Elective repair of infrarenal abdominal aortic aneurysm (AAA) carries a mortality of 4-8% and there is a substantial incidence of serious non-lethal complications. During surgery there is a situation of relative ischaemia and subsequent reperfusion of the lower part of the body. LÄS MER

  5. 9. Pro- and anticoagulant mechanisms in coronary artery disease. Clinical studies on factor VII and resistance to activated protein C

    Författare :Johan Holm; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein C; Factor VII; blood coagulation; myocardial infarction; APC resistance; Cardiovascular system; Kardiovaskulära systemet; warfarin;

    Sammanfattning : The triggering mechanism in myocardial infarction (MI) and unstable angina involves coronary thrombus formation following plaque rupture. Coagulation is initiated by tissue factor that activates factor VII (FVII), and is inhibited by protein C and its co-factor protein S. LÄS MER

  7. 10. Diabetic skin microangiopathy : studies on pathogenesis and treatment

    Författare :Majid Kalani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Diabetes mellitus; chronic foot ulcers; skin microcirculation; peripheral arterial occlusive disease; blood coagulation; fibrinolysis; fibrin gel structure; low molecular weight heparin; dalteparin.;

    Sammanfattning : Background: Most of late diabetic complications have their basis in a disturbed microcirculation, i.e. diabetic microangiopathy. LÄS MER