Sökning: "proteomik"

Visar resultat 1 - 5 av 57 avhandlingar innehållade ordet proteomik.

  1. 1. Identification of tissue biomarkers of prognostic significance in pancreatic cancer

    Detta är en avhandling från Lund University: Faculty of Medicine

    Författare :Dingyuan Hu; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic cancer; proteomics; mass spectrometry; Biomarkers; prognosis; CLCA1; pankreascancer; proteomik; masspektrometri; biomarkörer; prognos; CLCA1;

    Sammanfattning : Background: Pancreatic cancer is the third leading cause of cancer-related mortality. Lack of early detection strategies and therapeutic resistance are main contributors to the poor prognosis. Unfortunately, there are no tissue biomarkers available for the prognosis of pancreatic cancer in routine clinical use. LÄS MER

  2. 2. Lipoproteomics A New Approach to the Identification and Characterization of Proteins in LDL and HDL

    Detta är en avhandling från Institutionen för molekylär och klinisk medicin

    Författare :Helen Karlsson; Linköpings universitet.; Linköpings universitet.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LDL; HDL; Proteomik; Atheroskleros; Masspektrometri; 2-DE; MEDICINE Morphology; cell biology; pathology Pathology Molecular medicine; MEDICIN Morfologi; cellbiologi; patologi Patologi Molekylär medicin;

    Sammanfattning : A proteomic approach was applied to examine the protein composition of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) in humans. LDL and HDL were isolated by density gradient ultracentrifugation, and proteins were separated with twodimensional gel electrophoresis (2-DE) and identified with peptide mass fingerprinting, using matrix-assisted laser desorption/ionization-time of flight mass spectrometry, and with amino acid sequencing using electrospray ionization tandem mass spectrometry. LÄS MER

  3. 3. Proteomic Analysis of Urinary Bladder Cancer Aiming for Novel Biomarkers

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mårten Lindén; Uppsala universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; urine; APOE; FGB; GAL1; LRG1; POLR1E; SERPINA1; STMN1; TOP2A; biomarker; diagnostic biomarker; prognostic biomarker; predictive biomarker; mass spectrometry; western blot; dot blot; immunohistochemistry; IHC; tissue microarray; TMA; urothelium; antibody; antibody-based; urinblåsecancer; biomarkör; diagnos; prognos; urin; proteomik; masspektrometri; immunohistokemi; antikroppar; Molecular Biology; Molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Urinary bladder cancer is a heterogeneous disease appearing in different forms, e.g. non-muscle invasive and muscle invasive. For all variants, the expression of proteins is interesting to analyze for diagnostic, predictive, prognostic and drug targeting purposes, since it reflects the altered gene expression causing the cancer. LÄS MER

  4. 4. Interaction engineered three-helix bundle domains for protein recovery and detection

    Detta är en avhandling från Stockholm : KTH

    Författare :Tove Alm; KTH.; [2010]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ABD; Zbasic; albumin; protein engineering; phage display; staphylococcal display; inclusion bodies; refolding; proteomics; orthogonal affinity purification; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik; TECHNOLOGY Bioengineering Immunology engineering; TEKNIKVETENSKAP Bioteknik Immunteknik;

    Sammanfattning : HTML clipboard The great advances in DNA technology, e.g. sequencing and recombinant DNA techniques, have given us the genetic information and the tools needed to effectively produce recombinant proteins. Recombinant proteins are valuable means in biotechnological applications and are also emerging as alternatives in therapeutic applications. LÄS MER

  5. 5. Metabolic engineering strategies to increase n-butanol production from cyanobacteria

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Josefine Anfelt; KTH.; [2016]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; cyanobacteria; metabolic engineering; biofuels; butanol; synthetic scaffold; CRISPRi; solvent tolerance; Biotechnology; Bioteknologi;

    Sammanfattning : The development of sustainable replacements for fossil fuels has been spurred by concerns over global warming effects. Biofuels are typically produced through fermentation of edible crops, or forest or agricultural residues requiring cost-intensive pretreatment. LÄS MER