Sökning: "proteolysis"

Visar resultat 6 - 10 av 144 avhandlingar innehållade ordet proteolysis.

  1. 6. Intracellular systems for characterization and engineering of proteases and their substrates

    Författare :George Kostallas; Stefan Ståhl; Patrik Samuelson; Matthew DeLisa; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; proteases; flow cytometry; GFP; CAT; protein engineering; ssrA; ClpXP; tobacco etch virus; TEV; site-specific; high-throughput; selection; proteolysis; libraries; Bioengineering; Bioteknik; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : Over the years, the view on proteases as relatively non-specific protein degradation enzymes, mainly involved in food digestion and intracellular protein turnover, has shifted and they are now recognized as key regulators of many biological processes that determine the fate of a cell. Besides their biological role, proteases have emerged as important tools in various biotechnical, industrial and medical applications. LÄS MER

  3. 7. Design of enzymatic systems for the modification of cellulose fiber surfaces

    Författare :Malin Gustavsson; KTH; []
    Nyckelord :Candida antarctica lipase B; Pichia pastoris; cellulose-binding module; proteolysis; carbohydrate ester; xyloglucan endotransglycosylase; fiber modification;

    Sammanfattning : This thesis describes the design of enzymatic systems forthe modification of cellulose fiber surfaces. A single-enzymeapproach employed a conjugate between theNeocallimastix patriciarumCel6A cellulose-bindingmodule and lipase B fromCandida antarctica(CBM-CALB) to enhance theaccessibility of the enzyme to the target hydroxyl groups. LÄS MER

  4. 8. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

    Författare :Lukas Boge; Martin Andersson; Lovisa Ringstad; RISE; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid crystals; liquid crystalline nanoparticles; cubosome; hexosome; phase behavior; antimicrobial peptide; AMP; glycerol monooleate; proteolysis; antimicrobial effect; antimicrobial resistance; bacterial membrane; membrane interaction; infection; topical delivery; pulmonary delivery;

    Sammanfattning : The development of antimicrobial resistance is a great challenge within health sectors worldwide. Thus, demand for new, efficient treatments is urgent in order to treat various bacterial infections. Antimicrobial peptides (AMPs) are a group of antibiotics that have gained more and more attraction in the past decade. LÄS MER

  5. 9. Design of substrate induced transcription for control of recombinant protein production in Escherichia coli

    Författare :Maria Boström; KTH; []
    Nyckelord :Escherichia coli; substrate induced promoters; fed-batch processe; maltose operon; solubility; proteolysis; inclusion body formation;

    Sammanfattning : .... LÄS MER

  7. 10. DnaK complex formation and proteolysis : effects on recombinant proteins produced in Escherichia coli

    Författare :Kristina Gustavsson; KTH; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER