Sökning: "protein-protein interactions"

Visar resultat 16 - 20 av 187 avhandlingar innehållade orden protein-protein interactions.

  1. 16. Characterization and Engineering of Protein-Protein Interactions Involving PDZ Domains

    Författare :Andreas Karlsson; Per Jemth; Daniel Otzen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; intrinsically disordered protein regions; PDZ domain; binding kinetics; protein engineering; interaction mechanism; specificity; PDZbody; Chemistry with specialization in Biophysics; Kemi med inriktning mot biofysik;

    Sammanfattning : The work presented in this thesis has contributed with knowledge to several aspects of protein-protein interaction involving PDZ domains. A substantial amount of our proteome contains regions that are intrinsically disordered but fold upon ligand interaction. LÄS MER

  3. 17. Counter-current distribution of interacting molecules : simulation of distribution behaviour and application to protein-protein interactions

    Författare :Lars Backman; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Associations of biological macromolecules with other macromolecules, with larger assemblies of macromolecules and with themselves are widely encountered phenomena. In principle, these interactions can be studied with any method able to differentiate between free molecules and complexes formed. LÄS MER

  4. 18. Computational Prediction and Analysis of Protein-Carbohydrate and Protein-Protein Interactions

    Författare :Ashok Krishna Chaitanya Koppisetty; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Arylsulfatase-A; Norovirus VA387; Molecular Dynamics; Saposin B; Computational Docking;

    Sammanfattning : The structure and energetics of protein-carbohydrate and protein-protein interactions are of great interest due to their importance in many biological phenomena. Two cases of protein-carbohydrate interactions and one case of protein-protein interactions were predicted and analyzed using existing computational methods. LÄS MER

  5. 19. Identification and characterization of protein-protein interactions in the nuclear envelope

    Författare :Balaje Vijayaraghavan; Einar Hallberg; Katherine Wilson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nuclear envelope; Samp1; Emerin; Ran and transmembrane proteins; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : The nuclear envelope forms the interface between the nucleus and the cytoplasm. The nuclear envelope consists of the two concentric lipid membranes, the nuclear pores and the nuclear lamina. The inner nuclear membrane contains hundreds of unique transmembrane proteins showing high tissue diversity. LÄS MER

  7. 20. Protein and lipid interactions within the respiratory chain : Studies using membrane-mimetic systems

    Författare :Tobias Nilsson; Peter Brzezinski; Petra Hellwig; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cytochrome c oxidase; ATP synthase; Bioenergetics; membrane-mimetics; Rcf1; liposomes; oxidative phosphorylation; lipids; protein-protein interactions; Biochemistry; biokemi;

    Sammanfattning : Energy conversion from nutrients to ATP is a vital process in cells. The process, called oxidative phosphorylation (OXPHOS) is performed by a combination of membrane-bound proteins. These proteins have been studied in great detail in the past, however much is still unknown about how they interact with each other. LÄS MER