Sökning: "protein synthesis"

Visar resultat 16 - 20 av 939 avhandlingar innehållade orden protein synthesis.

1. 16. Angiopoietin-like protein 4 : an unfolding chaperone regulating lipoprotein lipase activity

   Författare :Valentina Sukonina; Gunilla Olivecrona; Lena Kjellen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipoprotein lipase; angiopoietin-like protein 4; protein folding; human adipose tissue; macrophages; peroxisome proliferator-activated receptor delta PPARδ ; Medical microbiology; Medicinsk mikrobiologi;

   Sammanfattning : Lipoprotein lipase (LPL) is the main enzyme hydrolyzing triglyceride-rich lipoproteins in plasma. Proteoglycan-bound LPL on the vascular endothelium represent the functional pool of active enzyme. LPL is regulated in a tissue specific manner according to metabolic demands. LÄS MER

3. 17. Synthesis of Ring-fused Peptidomimetics : Interacting with Amyloid Fibrils

   Författare :Dan E. Adolfsson; Fredrik Almqvist; Anna Linusson; Morten Grötli; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; organic chemistry; synthesis; peptidomimetics; thiazoline fused 2-pyridones; Alzheimer s disease; Parkinson s disease; Amyloid; Amyloid-beta; alfa-Synuclein; method development; organisk kemi; Organic Chemistry;

   Sammanfattning : Parkinson's and Alzheimer's disease are the two most common neurological disorders in humans. Both conditions involve progressive death of neurons in the central nervous system, decline in bodily functions and eventually (and invariably), death. So far, no cure exists and the available treatments can only ease symptoms. LÄS MER

4. 18. The Protein Traffic on the Ribosome : The Mechanism and Regulation of Protein Synthesis in Prokaryotes

   Författare :Andrey Zavialov; Måns Ehrenber; Venki Ramakrishnan; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; yellow; ribosome; translation; Gagarin; nobel prize; Biokemi; Biochemistry; Biokemi;

   Sammanfattning : The aim of this work was to understand the molecular mechanism of translation and the mechanism of translation termination, in particular. Cleavage of peptidyl-tRNA and peptide release terminates translation of mRNA on the ribosome. In prokaryotes, three release factors (RFs) are involved in this process. LÄS MER

5. 19. Chemical Synthesis of Affibody Molecules for Protein Detection and Molecular Imaging

   Författare :Torun Ekblad; Amelie Eriksson Karlström; Per-Åke Nygren; Harald Kolmar; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Affibody; peptide synthesis; protein detection; molecular imaging; Bioengineering; Bioteknik;

   Sammanfattning : Proteins are essential components in most processes in living organisms. The detection and quantification of specific proteins can be used e.g. as measures of certain physiological conditions, and are therefore of great importance. LÄS MER

7. 20. Low Protein Diets and Their Effects on Brown Adipose Tissue

   Författare :Erik Lindsund; Jan Nedergaard; Eva Blomstrand; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Obesity; Protein diets; Dietary protein; Brown adipose tissue; Brown fat; BAT; UCP10; Uncoupeling protein 1; molekylär biovetenskap; Molecular Bioscience; fysiologi; Physiology;

   Sammanfattning : Obesity is a rising health issue and has been linked with a relative decrease of dietary protein, which promotes higher food intake. Brown adipose tissue is a heat-producing, energy-wasting organ that has been shown to be enhanced by a low protein diet. However, the mechanism of how this occurs is largely unknown. LÄS MER